Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14915916 | 0.82 | BTK (0.39) | BTK | |
| SCHEMBL14915915 | 0.82 | BTK (0.39) | BTK | |
| SCHEMBL14912700 | 0.82 | BTK (0.39) | BTK | |
| SCHEMBL14915354 | 0.80 | BTK (0.42) | BTK | |
| SCHEMBL18759181 | 0.80 | BTK (0.37) | BTK | |
| SCHEMBL18759182 | 0.80 | BTK (0.37) | BTK | |
| SCHEMBL1392784 | 0.79 | BTK (0.38) | BTK | |
| SCHEMBL1393493 | 0.78 | BTK (0.40) | BTK | |
| SCHEMBL1393847 | 0.77 | BTK (0.47) | BTK | |
| SCHEMBL14912227 | 0.77 | BTK (0.39) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611790-B1 | PYRIDINONES/PYRAZINONES, METHOD OF MAKING, AND METHOD OF USE THEREOF | GILEAD CONNECTICUT INC (US) | 2015-11-04 | — | — | EP | disclosed |