Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18759181 | 1.00 | BTK (0.37) | BTK | |
| SCHEMBL14912700 | 0.89 | BTK (0.39) | BTK | |
| SCHEMBL14915915 | 0.89 | BTK (0.39) | BTK | |
| SCHEMBL14915916 | 0.89 | BTK (0.39) | BTK | |
| SCHEMBL14914814 | 0.80 | BTK (0.41) | BTK | |
| SCHEMBL17220299 | 0.80 | BTK (0.39) | BTK | |
| SCHEMBL14912227 | 0.78 | BTK (0.39) | BTK | |
| SCHEMBL14915354 | 0.78 | BTK (0.42) | BTK | |
| SCHEMBL14913137 | 0.77 | BTK (0.42) | BTK | |
| SCHEMBL28357589 | 0.77 | BTK (0.42) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773639-B1 | ALKYLATED PIPERAZINE COMPOUNDS AS INHIBITORS OF BTK ACTIVITY | HOFFMANN LA ROCHE (CH) | 2017-04-26 | — | — | EP | disclosed |