Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.44 |
| ▸ | HTR2C | P28335 | 5/20 | 0.44 |
| ▸ | HTR2B | P41595 | 5/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21723161 | 0.77 | HTR2A (0.41) | HTR2AHTR2CHTR2BCA1KDM1A | |
| SCHEMBL170738 | 0.76 | MEN1 (0.55) | HTR2CHTR2BKDM1ARCOR1KMT2A | |
| SCHEMBL170815 | 0.76 | MEN1 (0.55) | HTR2CHTR2BKDM1ARCOR1KMT2A | |
| SCHEMBL13272292 | 0.75 | HTR2A (0.56) | HTR2AHTR2CHTR2BKDM1ARCOR1 | |
| SCHEMBL7896331 | 0.75 | HTR2A (0.56) | HTR2AHTR2CHTR2BKDM1ARCOR1 | |
| SCHEMBL19444237 | 0.75 | HTR2A (0.56) | HTR2AHTR2CHTR2BKDM1ARCOR1 | |
| SCHEMBL20835371 | 0.74 | HTR2A (0.35) | HTR2AHTR2CHTR2BCA1KDM1A | |
| SCHEMBL22451497 | 0.74 | HTR2A (0.35) | HTR2AHTR2CHTR2BCA1KDM1A | |
| SCHEMBL22451400 | 0.74 | HTR2A (0.35) | HTR2AHTR2CHTR2BCA1KDM1A | |
| SCHEMBL19803650 | 0.74 | HTR2A (0.35) | HTR2AHTR2CHTR2BCA1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |