⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9346378 | 0.87 | TSHR (0.39) | — | |
| SCHEMBL8791048 | 0.81 | — | — | |
| SCHEMBL21104804 | 0.80 | — | — | |
| SCHEMBL21104360 | 0.80 | — | — | |
| SCHEMBL17049773 | 0.80 | — | — | |
| SCHEMBL28080612 | 0.76 | CA12 (0.45) | — | |
| SCHEMBL8791010 | 0.74 | ADH1B (0.32) | — | |
| SCHEMBL103021 | 0.74 | — | — | |
| SCHEMBL4033445 | 0.73 | — | — | |
| SCHEMBL11434149 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853455-B2 | Process for preparing substituted 2-nitrobiphenyls | BASF SE (DE) | 2014-10-07 | — | — | US | disclosed |
| EP-2406210-A1 | PROCESS FOR PREPARING SUBSTITUTED 2-NITROBIPHENYLS | BASF SE (DE) | 2012-01-18 | — | — | EP | disclosed |
| US-20110319665-A1 | Process for Preparing Substituted 2-Nitrobiphenyls | BASF SE (DE) | 2011-12-29 | — | — | US | disclosed |
| WO-2010102980-A1 | PROCESS FOR PREPARING SUBSTITUTED 2-NITROBIPHENYLS | BASF SE (DE) | 2010-09-16 | — | — | WO | disclosed |
| US-5637255-A | OPTICALLY ACTIVE FORM, USED FOR OPTICAL OR ELECTROOPTICAL DISPLYING; HIGH TWISTING; DOPANT | ROLIC AG (CH) | 1997-06-10 | — | — | US | disclosed |
| EP-0534258-B1 | Chiral oxazolines as dopants for liquid crystals mixtures | HOFFMANN LA ROCHE (CH) | 1997-05-21 | — | — | EP | disclosed |
| US-5518653-A | LIQUID CRYSTAL | HOFFMANN-LA ROCHE INC. (US) | 1996-05-21 | — | — | US | disclosed |
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| EP-0410233-B1 | (4-Arylbutyl) cyclohexane derivatives | HOFFMANN LA ROCHE (CH) | 1995-11-15 | — | — | EP | disclosed |
| EP-0441213-B1 | Chiral dioxolanes | HOFFMANN LA ROCHE (CH) | 1995-09-13 | — | — | EP | disclosed |
| US-5204018-A | LIQUID CRYSTALS | HOFFMANN-LA ROCHE INC. (US) | 1993-04-20 | — | — | US | disclosed |
| WO-1993007234-A1 | HALOVINYL-DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-15 | — | — | WO | disclosed |
| EP-0534258-A1 | Chiral oxazolines as dopants for liquid crystals mixtures | F. HOFFMANN-LA ROCHE AG (CH) | 1993-03-31 | — | — | EP | disclosed |
| EP-0457105-A1 | Chiral dioxanes as components of liquid crystal mixtures | F. HOFFMANN-LA ROCHE AG (CH) | 1991-11-21 | — | — | EP | disclosed |
| EP-0442306-A2 | (4E-cyclohexyl-3-butenyl)phenyl derivatives | F. Hoffmann-La Roche AG (CH) | 1991-08-21 | — | — | EP | disclosed |
| EP-0441213-A2 | Chiral dioxolanes | F. HOFFMANN-LA ROCHE AG (CH) | 1991-08-14 | — | — | EP | disclosed |
| US-5032312-A | Liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1991-07-16 | — | — | US | disclosed |
| EP-0410233-A2 | (4-Arylbutyl) cyclohexane derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-01-30 | — | — | EP | disclosed |
| EP-0393501-A1 | Liquid crystal components with a trans-3-cyclohexylallyloxy group | F. HOFFMANN-LA ROCHE AG (CH) | 1990-10-24 | — | — | EP | disclosed |
| EP-0344557-A2 | Liquid crystal components with a trimethylenoxy group | F. HOFFMANN-LA ROCHE AG (CH) | 1989-12-06 | — | — | EP | disclosed |