Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 8/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.53 |
| ▸ | TUBB | P07437 | 7/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.53 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18540746 | 1.00 | TUBB1 (0.53) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17224317 | 1.00 | TUBB1 (0.53) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17224265 | 0.85 | PTGS1 (0.56) | ALDH1A1CYP3A4PTGS1PTGS2MEN1 | |
| SCHEMBL18540732 | 0.85 | PTGS1 (0.56) | ALDH1A1CYP3A4PTGS1PTGS2MEN1 | |
| SCHEMBL17224266 | 0.85 | PTGS1 (0.56) | ALDH1A1CYP3A4PTGS1PTGS2MEN1 | |
| SCHEMBL11799835 | 0.81 | ALDH1A1 (0.61) | ALDH1A1CYP3A4PTGS1PTGS2MEN1 | |
| SCHEMBL11799840 | 0.81 | ALDH1A1 (0.61) | ALDH1A1CYP3A4PTGS1PTGS2MEN1 | |
| SCHEMBL10349412 | 0.80 | ALDH1A1 (0.52) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL18540717 | 0.79 | PTGS1 (0.59) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17224400 | 0.79 | PTGS1 (0.59) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3137554-A1 | AZOARYLS AS REVERSIBLY MODULATABLE TUBULIN INHIBITORS | Ecole Normale Superieure De Lyon (FR) | 2017-03-08 | — | — | EP | claimed |
| US-20170051149-A1 | AZOARYLS AS REVERSIBLY MODULATABLE TUBULIN INHIBITORS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-02-23 | — | — | US | claimed |
| WO-2015166295-A1 | AZOARYLS AS REVERSIBLY MODULATABLE TUBULIN INHIBITORS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2015-11-05 | — | — | WO | claimed |
| EP-3137554-A1 | AZOARYLS AS REVERSIBLY MODULATABLE TUBULIN INHIBITORS | Ecole Normale Superieure De Lyon (FR) | 2017-03-08 | — | — | EP | disclosed |
| US-20170051149-A1 | AZOARYLS AS REVERSIBLY MODULATABLE TUBULIN INHIBITORS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-02-23 | — | — | US | disclosed |
| WO-2015166295-A1 | AZOARYLS AS REVERSIBLY MODULATABLE TUBULIN INHIBITORS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2015-11-05 | — | — | WO | disclosed |