Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 9/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 9/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 9/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17224769 | 0.89 | ATM (0.34) | ATMCSNK2A2CSNK2BCSNK2A1MAPT | |
| SCHEMBL17224763 | 0.85 | KDM4E (0.37) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL17224781 | 0.84 | CSNK2A2 (0.41) | ATMCSNK2A2CSNK2BCSNK2A1MAPT | |
| SCHEMBL17224768 | 0.83 | KDM4E (0.36) | ATMKDM4EMAPTALDH1A1GAA | |
| SCHEMBL17224792 | 0.83 | MAPT (0.39) | ATMKDM4EMAPTALDH1A1GAA | |
| SCHEMBL17224793 | 0.81 | KDM4E (0.42) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL23398242 | 0.75 | KDM4E (0.36) | ATMCSNK2A2CSNK2BCSNK2A1KDM4E | |
| SCHEMBL17224764 | 0.75 | KDM4E (0.39) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL23628499 | 0.75 | PREP (0.34) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL18797098 | 0.74 | KDM4E (0.37) | KDM4EMAPTALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3137456-B1 | PYRIDAZINONE HERBICIDES | FMC CORP (US) | 2021-06-02 | — | — | EP | claimed |
| CN-106458926-B | Pyridazinone herbicides | FMC公司 | 2020-01-03 | — | — | CN | claimed |
| EP-3137456-A1 | PYRIDAZINONE HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2017-03-08 | — | — | EP | claimed |
| US-20170050953-A1 | PYRIDAZINONE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2017-02-23 | — | — | US | claimed |
| WO-2015168010-A1 | PYRIDAZINONE HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-11-05 | — | — | WO | claimed |
| CN-111018790-B | Pyridazinone herbicides | FMC公司 | 2023-09-19 | — | — | CN | disclosed |
| EP-3865480-A1 | HYDRAZINE DERIVATIVES | FMC Corporation (US) | 2021-08-18 | — | — | EP | disclosed |
| EP-3137456-B1 | PYRIDAZINONE HERBICIDES | FMC CORP (US) | 2021-06-02 | — | — | EP | disclosed |
| CN-111018790-A | Pyridazinone herbicides | FMC公司 | 2020-04-17 | — | — | CN | disclosed |
| US-10597388-B2 | Pyridazinone herbicides | FMC CORPORATION (US) | 2020-03-24 | — | — | US | disclosed |
| CN-106458926-B | Pyridazinone herbicides | FMC公司 | 2020-01-03 | — | — | CN | disclosed |
| US-20190016712-A1 | PYRIDAZINONE HERBICIDES | FMC CORPORATION | 2019-01-17 | — | — | US | disclosed |
| US-10118917-B2 | Pyridazinone herbicides | FMC CORPORATION | 2018-11-06 | — | — | US | disclosed |
| EP-3137456-A1 | PYRIDAZINONE HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2017-03-08 | — | — | EP | disclosed |
| US-20170050953-A1 | PYRIDAZINONE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2017-02-23 | — | — | US | disclosed |
| WO-2015168010-A1 | PYRIDAZINONE HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-11-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190016712-A1 | PYRIDAZINONE HERBICIDES | CBR3, NOX5, NR5A2 | ATM 4170/4885CSNK2A2 1987/4885CSNK2B 1806/4885 |
| US-20170050953-A1 | PYRIDAZINONE HERBICIDES | CBR3, NOX5, NR5A2 | ATM 4170/4885CSNK2A2 1987/4885CSNK2B 1806/4885 |
| US-10118917-B2 | Pyridazinone herbicides | CBR3, NOX5, NR5A2 | ATM 4170/4885CSNK2A2 1987/4885CSNK2B 1806/4885 |
| US-10597388-B2 | Pyridazinone herbicides | CBR3, NOX5, NR5A2 | ATM 4170/4885CSNK2A2 1987/4885CSNK2B 1806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.