Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 6/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 6/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23398238 | 0.84 | KDM4E (0.35) | KDM4EL3MBTL1ATMMEN1KMT2A | |
| SCHEMBL17224781 | 0.78 | CSNK2A2 (0.41) | ATMCSNK2A2CSNK2BCSNK2A1MEN1 | |
| SCHEMBL17224769 | 0.77 | ATM (0.34) | ATMCSNK2A2CSNK2BCSNK2A1MEN1 | |
| SCHEMBL17224767 | 0.75 | ATM (0.35) | KDM4EATMCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL23398251 | 0.67 | CSNK2A2 (0.36) | ATMCSNK2A2CSNK2BCSNK2A1MEN1 | |
| SCHEMBL17224744 | 0.63 | MCL1 (0.36) | KDM4EMAPT | |
| SCHEMBL17224772 | 0.61 | MAPT (0.48) | KDM4EATMCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL17224770 | 0.61 | ALDH1A1 (0.32) | KDM4EL3MBTL1ATMMEN1KMT2A | |
| SCHEMBL17224763 | 0.60 | KDM4E (0.37) | KDM4EMEN1KMT2ALMNAMAPT | |
| SCHEMBL17224757 | 0.60 | NQO1 (0.42) | KDM4EATMCSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3137456-B1 | PYRIDAZINONE HERBICIDES | FMC CORP (US) | 2021-06-02 | — | — | EP | claimed |