SCHEMBL17225486

SCHEMBL17225486

COc1nc2cc(C(=O)O)ccc2c2cnccc12

nearest known ligand 0.68

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 19/20 0.68
CSNK2B P67870 18/20 0.68
CSNK2A1 P68400 8/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10131366 0.81 CSNK2A1 (1.00) CSNK2A2CSNK2BCSNK2A1
SCHEMBL15486463 0.81 CSNK2A2 (0.69) CSNK2A2CSNK2BCSNK2A1
SCHEMBL10131357 0.80 CSNK2A2 (0.63) CSNK2A2CSNK2BCSNK2A1
SCHEMBL15493528 0.80 PARP1 (0.58) CSNK2A2CSNK2BCSNK2A1
SCHEMBL11932365 0.80 CSNK2A2 (0.67) CSNK2A2CSNK2BCSNK2A1
SCHEMBL26048829 0.79 CSNK2A2 (0.56) CSNK2A2CSNK2BCSNK2A1
SCHEMBL25293831 0.78 CSNK2A2 (1.00) CSNK2A2CSNK2BCSNK2A1
SCHEMBL10131670 0.78 CSNK2A1 (0.83) CSNK2A2CSNK2BCSNK2A1
SCHEMBL25287236 0.77 CSNK2A1 (0.81) CSNK2A2CSNK2BCSNK2A1
SCHEMBL25370051 0.77 PARP1 (0.54) CSNK2A2CSNK2BCSNK2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9176064-B2 Bisubstrate fluorescent probes for protein kinase CK2 UNIVERSITY OF TARTU (EE) 2015-11-03 US disclosed