SCHEMBL26048829

SCHEMBL26048829

CCCCCOCCOc1nc2cc(C(=O)O)ccc2c2cnccc12

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 19/20 0.56
CSNK2B P67870 19/20 0.56
PARP1 P09874 1/20 0.54
CSNK2A1 P68400 6/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26048832 0.92 CSNK2A2 (0.53) CSNK2A2CSNK2BPARP1CSNK2A1
SCHEMBL30694781 0.90 PARP1 (0.54) CSNK2A2CSNK2BPARP1CSNK2A1
SCHEMBL25370051 0.90 PARP1 (0.54) CSNK2A2CSNK2BPARP1CSNK2A1
SCHEMBL29900367 0.84 CSNK2A2 (0.49) CSNK2A2CSNK2BPARP1CSNK2A1
SCHEMBL25371343 0.84 CSNK2A2 (0.49) CSNK2A2CSNK2BPARP1CSNK2A1
SCHEMBL26049075 0.84 CSNK2A2 (0.49) CSNK2A2CSNK2BPARP1CSNK2A1
SCHEMBL15493528 0.83 PARP1 (0.58) CSNK2A2CSNK2BPARP1CSNK2A1
SCHEMBL25371037 0.83 CSNK2A2 (0.51) CSNK2A2CSNK2BPARP1CSNK2A1
SCHEMBL30694765 0.83 CSNK2A2 (0.51) CSNK2A2CSNK2BPARP1CSNK2A1
SCHEMBL26048836 0.82 CSNK2A2 (0.53) CSNK2A2CSNK2BPARP1CSNK2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250097-A1 BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF Apollo Therapeutics Limited (GB) 2023-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250097-A1 BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF CSNK1A1, CSNK1D, CSNK2A1 CSNK2A2 5/4885CSNK2B 8/4885PARP1 1944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.