Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 9/20 | 0.55 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.55 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.55 |
| ▸ | CDK2 | P24941 | 6/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129642 | 0.81 | CDK1 (0.68) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL10148680 | 0.79 | CDK1 (0.57) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL764036 | 0.78 | CDK1 (0.59) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| 9-Methylguanine SCHEMBL2787045 | 0.78 | CDK1 (0.59) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL6744537 | 0.76 | ADORA2A (0.55) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL12374282 | 0.75 | CDK1 (0.40) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL24021885 | 0.75 | CDK1 (0.53) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL13485346 | 0.75 | CDK1 (0.53) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL24021902 | 0.75 | CDK1 (0.53) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL14566583 | 0.75 | CDK1 (0.53) | CDK1CCNB1CCNE1CDK2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020154917-A1 | PHOSPHATE AND PHOSPHONATE BASED COMPOUNDS OF 6-THIO-2'-DEOXYGUANOSINE AS ANTI-CANCER AGENTS | MINGHUI PHARMACEUTICAL (SHANGHAI) LIMITED (CN) | 2020-08-06 | — | — | WO | disclosed |
| US-9174990-B2 | 2-amino-9-[(2-hydroxymethyl) cyclopropylidenemethyl] purines as antiviral agents | WAYNE STATE UNIVERSITY (US) | 2015-11-03 | — | — | US | disclosed |