Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.55 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.53 |
| ▸ | CDK1 | P06493 | 3/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.51 |
| ▸ | CDK2 | P24941 | 3/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3922885 | 0.85 | CDK1 (0.71) | ADORA2ASLC29A1CDK1CCNB1CCNE1 | |
| SCHEMBL5172274 | 0.82 | ADORA2A (0.55) | ADORA2ASLC29A1CDK1CCNB1CCNE1 | |
| SCHEMBL20820140 | 0.79 | CDK1 (0.68) | ADORA2ASLC29A1CDK1CCNB1CCNE1 | |
| SCHEMBL8348467 | 0.79 | CTSL (0.57) | ADORA2ASLC29A1CDK1CCNB1CCNE1 | |
| SCHEMBL4845463 | 0.78 | CDK1 (0.53) | ADORA2ASLC29A1CDK1CCNB1CCNE1 | |
| SCHEMBL4849504 | 0.78 | TLR9 (0.51) | ADORA2ASLC29A1CDK1CCNB1CCNE1 | |
| SCHEMBL4847394 | 0.78 | HSP90AB1 (0.53) | ADORA2ASLC29A1CDK1CCNB1CCNE1 | |
| SCHEMBL4848376 | 0.78 | CDK1 (0.50) | ADORA2ASLC29A1CDK1CCNB1CCNE1 | |
| SCHEMBL12963419 | 0.78 | CTSL (0.59) | ADORA2ASLC29A1CDK1CCNB1CCNE1 | |
| SCHEMBL7199849 | 0.78 | CCNE1 (0.44) | ADORA2ASLC29A1CDK1CCNB1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040260038-A1 | Maleic acid derivative and curable composition containing the same | TEH YOKOHAMA RUBBER CO., LTD. (JP) | 2004-12-23 | — | — | US | disclosed |