Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.56 |
| ▸ | DRD3 | P35462 | 12/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13630110 | 0.86 | DRD2 (0.59) | DRD2DRD3HTR2AHTR1ADRD1 | |
| SCHEMBL4481761 | 0.86 | DRD2 (0.59) | DRD2DRD3HTR2AHTR1ADRD1 | |
| SCHEMBL13630270 | 0.85 | DRD3 (0.61) | DRD2DRD3HTR2AHTR1ADRD1 | |
| SCHEMBL4489914 | 0.85 | DRD3 (0.61) | DRD2DRD3HTR2AHTR1ADRD1 | |
| SCHEMBL13629995 | 0.85 | DRD2 (0.59) | DRD2DRD3HTR2AHTR1ADRD1 | |
| SCHEMBL13630453 | 0.85 | DRD2 (0.58) | DRD2DRD3HTR2AHTR1ADRD1 | |
| SCHEMBL4487373 | 0.85 | DRD2 (0.58) | DRD2DRD3HTR2AHTR1ADRD1 | |
| SCHEMBL4488376 | 0.85 | DRD2 (0.59) | DRD2DRD3HTR2AHTR1ADRD1 | |
| SCHEMBL13630175 | 0.85 | DRD2 (0.59) | DRD2DRD3HTR2AHTR1ADRD1 | |
| SCHEMBL13630111 | 0.84 | DRD3 (0.54) | DRD2DRD3HTR2AHTR1ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038268-B1 | CARBONYLATED (AZA)CYCLOHEXANES AS DOPAMINE D3 RECEPTOR LIGANDS | BIOPROJET SOC CIV (FR) | 2015-11-04 | — | — | EP | disclosed |