SCHEMBL1722741

SCHEMBL1722741

CC(C)=CCC/C(C)=C/CNC(=O)CCC(=O)NC/C=C(\C)CCC=C(C)C

nearest known ligand 0.71

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FNTA P49354 8/20 0.71
FNTB P49356 6/20 0.71
PGGT1B P53609 3/20 0.69
TRPV1 Q8NER1 6/20 0.66
TRPA1 O75762 1/20 0.63
KMT2A Q03164 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1723041 1.00 FNTA (0.71) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL16770097 0.95 FNTA (0.66) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL15161516 0.93 FNTA (0.64) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL8940673 0.92 FNTA (0.67) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL8940669 0.92 FNTA (0.67) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL12511782 0.91 FNTA (0.66) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL13146186 0.91 FNTA (0.66) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL1724882 0.90 FNTA (0.61) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL1724883 0.90 FNTA (0.61) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL19734473 0.90 FNTA (0.68) FNTAFNTBPGGT1BTRPV1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2399899-B1 Geranyl compounds OHGEN RES LAB LTD (JP) 2013-08-07 EP disclosed
EP-2404894-A1 Mevalonic Acid Derivatives Ohgen Research Laboratories Ltd. (JP) 2012-01-11 EP disclosed
EP-2399899-A1 Geranyl compounds Ohgen Research Laboratories Ltd. (JP) 2011-12-28 EP disclosed
EP-2399900-A1 Geranyl compounds Ohgen Research Laboratories Ltd. (JP) 2011-12-28 EP disclosed
US-7579376-B2 N-geranoyltyrosine and N-geranoylcycteine as excellant antitumor and anticarcinogenic agents OHGEN RESEARCH LABORATORIES, LTD. (JP) 2009-08-25 US disclosed
US-7579376-B2 N-geranoyltyrosine and N-geranoylcycteine as excellant antitumor and anticarcinogenic agents OHGEN RESEARCH LABORATORIES, LTD. (JP) 2009-08-25 US disclosed
US-7553820-B2 Mevalonic acid derivatives OHGEN RESEARCH LABORATORIES, LTD. (JP) 2009-06-30 US disclosed
US-7553820-B2 Mevalonic acid derivatives OHGEN RESEARCH LABORATORIES, LTD. (JP) 2009-06-30 US disclosed
US-7507765-B2 Geranyl compounds OHGEN RESEARCH LABORATORIES, LTD. (JP) 2009-03-24 US disclosed
US-7507765-B2 Geranyl compounds OHGEN RESEARCH LABORATORIES, LTD. (JP) 2009-03-24 US disclosed
US-20080119556-A1 Geranly compounds AKIYAMA KIYOSHI 2008-05-22 US disclosed
US-20080113939-A1 Geranyl compounds AKIYAMA KIYOSHI 2008-05-15 US disclosed
US-7125852-B2 Geranyl compounds OHGEN RESEARCH LABORATORIES, LTD. (JP) 2006-10-24 US disclosed
EP-1471052-A1 GERANYL COMPOUNDS Ohgen Research Laboratories Ltd. (JP) 2004-10-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080113939-A1 Geranyl compounds GGPS1, FNTA, CCNE2 FNTA 2/4885FNTB 64/4885PGGT1B 30/4885
US-20080119556-A1 Geranly compounds GMNN, TP53, MCL1 FNTA 406/4885FNTB 1727/4885PGGT1B 470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.