SCHEMBL1724883

SCHEMBL1724883

CC(C)=CCCC(C)=CCNC(=O)CCC(=O)C(=O)NCC=C(C)CCC=C(C)C

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FNTA P49354 8/20 0.61
FNTB P49356 6/20 0.61
PGGT1B P53609 3/20 0.58
TRPV1 Q8NER1 6/20 0.57
TRPA1 O75762 1/20 0.54
GGPS1 O95749 2/20 0.46
FDPS P14324 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1724882 1.00 FNTA (0.61) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL1722741 0.90 FNTA (0.71) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL1723041 0.90 FNTA (0.71) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL4982496 0.88 TRPA1 (0.54) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL4982490 0.86 FNTA (0.59) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL4982493 0.86 TRPA1 (0.52) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL16770097 0.85 FNTA (0.66) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL2568553 0.85 TRPA1 (0.65) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL2571319 0.85 TRPA1 (0.65) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL2568549 0.85 TRPA1 (0.65) FNTAFNTBPGGT1BTRPV1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2399899-B1 Geranyl compounds OHGEN RES LAB LTD (JP) 2013-08-07 EP disclosed
EP-2404894-A1 Mevalonic Acid Derivatives Ohgen Research Laboratories Ltd. (JP) 2012-01-11 EP disclosed
EP-2399900-A1 Geranyl compounds Ohgen Research Laboratories Ltd. (JP) 2011-12-28 EP disclosed
EP-2399899-A1 Geranyl compounds Ohgen Research Laboratories Ltd. (JP) 2011-12-28 EP disclosed
US-7579376-B2 N-geranoyltyrosine and N-geranoylcycteine as excellant antitumor and anticarcinogenic agents OHGEN RESEARCH LABORATORIES, LTD. (JP) 2009-08-25 US disclosed
US-7553820-B2 Mevalonic acid derivatives OHGEN RESEARCH LABORATORIES, LTD. (JP) 2009-06-30 US disclosed
US-7507765-B2 Geranyl compounds OHGEN RESEARCH LABORATORIES, LTD. (JP) 2009-03-24 US disclosed
US-7125852-B2 Geranyl compounds OHGEN RESEARCH LABORATORIES, LTD. (JP) 2006-10-24 US disclosed
EP-1471052-A1 GERANYL COMPOUNDS Ohgen Research Laboratories Ltd. (JP) 2004-10-27 EP disclosed