Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17227683 | 0.84 | TP53 (0.50) | PDPK1TSHRTP53ALDH1A1 | |
| SCHEMBL17223593 | 0.70 | ERCC1 (0.46) | PDPK1RAB9AARL3MBTL1PRKDC | |
| SCHEMBL19002859 | 0.68 | PDPK1 (0.43) | PDPK1LCKFLT3MAP4K1TSHR | |
| Potassium Ion SCHEMBL6436227 | 0.67 | PDPK1 (0.42) | PDPK1FLT3TSHRHTTRAB9A | |
| SCHEMBL18641272 | 0.63 | HTR2C (0.49) | HTR3ATSHRRAB9A | |
| SCHEMBL17227776 | 0.63 | ALDH1A1 (0.47) | ACHEHTR3ATSHRHTTALDH1A1 | |
| SCHEMBL17227684 | 0.63 | ALDH1A1 (0.40) | HTR3ATSHRRAB9ANPC1TP53 | |
| SCHEMBL5437924 | 0.62 | SMN1; SMN2 (0.43) | PDPK1RAB9ANPC1L3MBTL1HPGD | |
| SCHEMBL17227682 | 0.61 | KMT2A (0.48) | ACHETSHRHTTALDH1A1 | |
| SCHEMBL31214324 | 0.61 | HRH4 (0.70) | BCHEACHEHTR3ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10174032-B2 | Heterocyclic compound classes for signaling modulation | SIGNALRX PHARMACEUTICALS, INC. (US) | 2019-01-08 | — | — | US | disclosed |
| US-20150315207-A1 | Novel Heterocyclic Compound Classes for Signaling Modulation | SIGNALRX PHARMACEUTICALS, INC. (US) | 2015-11-05 | — | — | US | disclosed |
| US-20150315207-A1 | Novel Heterocyclic Compound Classes for Signaling Modulation | SIGNALRX PHARMACEUTICALS, INC. (US) | 2015-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150315207-A1 | Novel Heterocyclic Compound Classes for Signaling Modulation | BRD3, BRPF3, BRD4 | PDPK1 34/4885LCK 624/4885FLT3 865/4885 |
| US-10174032-B2 | Heterocyclic compound classes for signaling modulation | BRD3, BRDT, BRPF3 | PDPK1 53/4885LCK 487/4885FLT3 825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.