Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15954244 | 1.00 | MAOB (0.40) | MAOBNFKB1NFKB2RELACYP19A1 | |
| SCHEMBL25201323 | 1.00 | MAOB (0.40) | MAOBNFKB1NFKB2RELACYP19A1 | |
| SCHEMBL17227883 | 0.87 | NFKB1 (0.38) | MAOBNFKB1NFKB2RELACYP19A1 | |
| SCHEMBL725410 | 0.87 | NFKB1 (0.38) | MAOBNFKB1NFKB2RELACYP19A1 | |
| SCHEMBL30315348 | 0.87 | NFKB1 (0.38) | MAOBNFKB1NFKB2RELACYP19A1 | |
| SCHEMBL17229229 | 0.87 | NFKB1 (0.38) | MAOBNFKB1NFKB2RELACYP19A1 | |
| SCHEMBL25188410 | 0.86 | NFKB1 (0.43) | MAOBNFKB1NFKB2RELACYP19A1 | |
| SCHEMBL25188411 | 0.86 | NFKB1 (0.43) | MAOBNFKB1NFKB2RELACYP19A1 | |
| SCHEMBL25194232 | 0.84 | MAOB (0.39) | MAOBNFKB1NFKB2RELACYP19A1 | |
| SCHEMBL25264499 | 0.84 | MEN1 (0.39) | NFKB1NFKB2RELAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10308624-B2 | Catalytic enantioselective synthesis of 2-aryl chromenes and related phosphoramidite ligands and catalyst compounds | NORTHWESTERN UNIVERSITY (US) | 2019-06-04 | — | — | US | disclosed |
| US-20180099943-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | NORTHWESTERN UNIVERSITY | 2018-04-12 | — | — | US | disclosed |
| US-20180099943-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | NORTHWESTERN UNIVERSITY | 2018-04-12 | — | — | US | disclosed |
| US-9840487-B2 | Catalytic enantioselective synthesis of 2-aryl chromenes and related phosphoramidite ligands and catalyst compounds | NORTHWESTERN UNIVERSITY (US) | 2017-12-12 | — | — | US | disclosed |
| US-9840487-B2 | Catalytic enantioselective synthesis of 2-aryl chromenes and related phosphoramidite ligands and catalyst compounds | NORTHWESTERN UNIVERSITY (US) | 2017-12-12 | — | — | US | disclosed |
| US-20170217919-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | NORTHWESTERN UNIVERSITY | 2017-08-03 | — | — | US | disclosed |
| US-20170217919-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | NORTHWESTERN UNIVERSITY | 2017-08-03 | — | — | US | disclosed |
| US-9624190-B2 | Catalytic enantioselective synthesis of 2-aryl chromenes and related phosphoramidite ligands and catalyst compounds | NORTHWESTERN UNIVERSITY (US) | 2017-04-18 | — | — | US | disclosed |
| US-9624190-B2 | Catalytic enantioselective synthesis of 2-aryl chromenes and related phosphoramidite ligands and catalyst compounds | NORTHWESTERN UNIVERSITY (US) | 2017-04-18 | — | — | US | disclosed |
| US-20160221982-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | NORTHWESTERN UNIVERSITY | 2016-08-04 | — | — | US | disclosed |
| US-20160221982-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | NORTHWESTERN UNIVERSITY | 2016-08-04 | — | — | US | disclosed |
| US-9309217-B2 | Catalytic enantioselective synthesis of 2-aryl chromenes and related phosphoramidite ligands and catalyst compounds | NORTHWESTERN UNIVERSITY (US) | 2016-04-12 | — | — | US | disclosed |
| US-9309217-B2 | Catalytic enantioselective synthesis of 2-aryl chromenes and related phosphoramidite ligands and catalyst compounds | NORTHWESTERN UNIVERSITY (US) | 2016-04-12 | — | — | US | disclosed |
| US-20150315168-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-11-05 | — | — | US | disclosed |
| US-20150315168-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-11-05 | — | — | US | disclosed |
| CN-101921252-B | 1-oxa-benzo-heterocycle compound, synthesis method and application thereof | SHANGHAI INST ORGANIC CHEM | 2012-05-09 | — | — | CN | disclosed |
| CN-101921252-A | 1-oxa-benzo-heterocycle compound, synthesis method and application thereof | SHANGHAI INST ORGANIC CHEM | 2010-12-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217919-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | PNP, PPA1, CDS2 | MAOB 927/4885NFKB1 4690/4885NFKB2 3871/4885 |
| US-20160221982-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | PNP, PPA1, CDS2 | MAOB 927/4885NFKB1 4690/4885NFKB2 3871/4885 |
| US-10308624-B2 | Catalytic enantioselective synthesis of 2-aryl chromenes and related phosphoramidite ligands and catalyst compounds | PNP, PPA1, CDS2 | MAOB 927/4885NFKB1 4690/4885NFKB2 3871/4885 |
| US-20150315168-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | PNP, PPA1, CDS2 | MAOB 927/4885NFKB1 4690/4885NFKB2 3871/4885 |
| US-20180099943-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | PNP, PPA1, CDS2 | MAOB 927/4885NFKB1 4690/4885NFKB2 3871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.