Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrylammonium SCHEMBL331298 | 0.81 | TSHR (0.53) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL27869205 | 0.78 | TSHR (0.57) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL36704 | 0.78 | TSHR (0.57) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Bromide SCHEMBL28431593 | 0.76 | SLC22A1 (0.43) | TSHR | |
| Tetrylammonium SCHEMBL28602155 | 0.75 | TSHR (0.53) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL3643966 | 0.75 | TSHR (0.53) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL331444 | 0.75 | TSHR (0.53) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| SCHEMBL172218 | 0.74 | BBOX1 (0.38) | — | |
| Hydrogen Sulfide SCHEMBL28046696 | 0.73 | — | — | |
| Tetrylammonium SCHEMBL8645725 | 0.73 | TSHR (0.50) | TSHRNFKB1KCNA1KDM4EPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9278909-B2 | Amide-extended crosslinking compounds and methods for use thereof | DESIGNER MOLECULES, INC. (US) | 2016-03-08 | — | — | US | disclosed |
| US-20130338313-A1 | AMIDE-EXTENDED CROSSLINKING COMPOUNDS AND METHODS FOR USE THEREOF | DESIGNER MOLECULES, INC. (US) | 2013-12-19 | — | — | US | disclosed |
| US-8513375-B2 | Imide-linked maleimide and polymaleimide compounds | DESIGNER MOLECULES, INC. | 2013-08-20 | — | — | US | disclosed |
| US-8304171-B2 | Plate making method of lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2012-11-06 | — | — | US | disclosed |
| EP-2082875-B1 | Lithographic printing plate precursor and plate making method using the precursor | FUJIFILM CORP (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20110130485-A1 | IMIDE-LINKED MALEIMIDE AND POLYMALEIMIDE COMPOUNDS | DESIGNER MOLECULES, INC. (US) | 2011-06-02 | — | — | US | disclosed |
| US-7884174-B2 | condensation of appropriate anhydrides with appropriate diamines to give amine terminated compounds, then condensed with excess maleic anhydride to yield imide-extended maleimide compounds | DESIGNER MOLECULES, INC. (US) | 2011-02-08 | — | — | US | disclosed |
| US-20100248142-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE MAKING METHOD THEREOF | FUJIFILM CORPORATION (JP) | 2010-09-30 | — | — | US | disclosed |
| US-20100075260-A1 | PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR | FUJIFILM CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
| US-20100055607-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE MAKING METHOD THEREOF | FUJIFILM CORPORATION (JP) | 2010-03-04 | — | — | US | disclosed |
| US-20090233222-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR | FUJIFILM CORPORATION (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-2082875-A1 | Lithographic printing plate precursor and plate making method thereof | FUJIFILM Corporation (JP) | 2009-07-29 | — | — | EP | disclosed |
| US-7560599-B2 | Method for preparing polymethoxymethylal | LANZHOU INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2009-07-14 | — | — | US | disclosed |
| US-20090036715-A1 | METHOD FOR PREPARING POLYMETHOXYMETHYLAL | LANZHOU INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2009-02-05 | — | — | US | disclosed |
| US-20080075961-A1 | Imide-linked maleimide and polymaleimide compounds | DESIGNER MOLECULES, INC. | 2008-03-27 | — | — | US | disclosed |
| US-7208566-B2 | Imide-linked maleimide and polymaleimide compounds | DESIGNER MOLECULES, INC. (US) | 2007-04-24 | — | — | US | disclosed |
| EP-1620495-A4 | IMIDE-LINKED MALEIMIDE AND POLYMALEIMIDE COMPOUNDS | ADVANCED APPLIED ADHESIVES (US) | 2006-06-14 | — | — | EP | disclosed |
| EP-1620495-A2 | IMIDE-LINKED MALEIMIDE AND POLYMALEIMIDE COMPOUNDS | Advanced Applied Adhesives (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004099331-A2 | IMIDE-LINKED MALEIMIDE AND POLYMALEIMIDE COMPOUNDS | ADVANCED APPLIED ADHESIVES (US) | 2004-11-18 | — | — | WO | disclosed |
| US-20040225026-A1 | Imide-linked maleimide and polymaleimide compounds | DESIGNER MOLECULES, INC. | 2004-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130485-A1 | IMIDE-LINKED MALEIMIDE AND POLYMALEIMIDE COMPOUNDS | MEN1, PBRM1, PAICS | TSHR 4587/4885NFKB1 2345/4885KCNA1 3946/4885 |
| US-20090036715-A1 | METHOD FOR PREPARING POLYMETHOXYMETHYLAL | TET3, TET2, TET1 | TSHR 4819/4885NFKB1 2665/4885KCNA1 2106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.