Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1722848 | 0.87 | BDKRB1 (0.92) | BDKRB1CCKBR | |
| SCHEMBL14686169 | 0.79 | BDKRB1 (1.00) | BDKRB1CCKBR | |
| SCHEMBL2517392 | 0.79 | BDKRB1 (1.00) | BDKRB1CCKBR | |
| SCHEMBL9597535 | 0.77 | CCKBR (0.72) | CCKBR | |
| SCHEMBL1713172 | 0.76 | BDKRB1 (0.91) | BDKRB1CCKBR | |
| SCHEMBL7597135 | 0.75 | CCKBR (0.58) | BDKRB1CCKBR | |
| SCHEMBL7597095 | 0.74 | CCKBR (0.56) | BDKRB1CCKBR | |
| SCHEMBL7593227 | 0.74 | BDKRB1 (0.82) | BDKRB1CCKBR | |
| SCHEMBL7586803 | 0.73 | BDKRB1 (0.88) | BDKRB1CCKBR | |
| SCHEMBL6949426 | 0.73 | CCKAR (0.76) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344176-A1 | USE OF BRADYKININ B1 RECEPTOR ANTAGONISTS IN INTESTINAL FIBROSIS TREATMENT | Jerini AG (DE) | 2011-07-20 | — | — | EP | claimed |
| WO-2010031577-A1 | USE OF BRADYKININ B1 RECEPTOR ANTAGONISTS IN INTESTINAL FIBROSIS TREATMENT | JERINI AG (DE) | 2010-03-25 | — | — | WO | claimed |
| EP-2344176-A1 | USE OF BRADYKININ B1 RECEPTOR ANTAGONISTS IN INTESTINAL FIBROSIS TREATMENT | Jerini AG (DE) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010031577-A1 | USE OF BRADYKININ B1 RECEPTOR ANTAGONISTS IN INTESTINAL FIBROSIS TREATMENT | JERINI AG (DE) | 2010-03-25 | — | — | WO | disclosed |