SCHEMBL17228972

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19985947	0.94	ESR2 (0.36)	ESR2AHRMAPTMEN1KMT2A
	SCHEMBL17228965	0.93	MAPT (0.35)	ESR2AHRMAPTMEN1KMT2A
	SCHEMBL17228979	0.92	ESR2 (0.36)	ESR2AHRMAPTMEN1KMT2A
	SCHEMBL26476573	0.89	PRKDC (0.36)	ESR2AHRMAPTMEN1KMT2A
	SCHEMBL17297486	0.88	ESR2 (0.36)	ESR2AHRMAPTMEN1KMT2A
	SCHEMBL23981138	0.88	ESR2 (0.33)	ESR2MAPTESR1TP53RXFP1
	SCHEMBL19985926	0.87	MAPT (0.34)	ESR2AHRMAPTMEN1KMT2A
	SCHEMBL22133229	0.87	ESR2 (0.32)	ESR2ESR1TP53
	SCHEMBL18687892	0.86	AHR (0.33)	ESR2AHRMAPTMEN1KMT2A
	SCHEMBL17405705	0.86	MAPT (0.35)	ESR2AHRMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.