Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16979299 | 0.93 | THRB (0.49) | PPARAPPARDTHRBHPGDL3MBTL1 | |
| SCHEMBL19302424 | 0.91 | THRB (0.50) | THRBMAPTNPC1TDP1HPGD | |
| SCHEMBL26750219 | 0.87 | THRB (0.55) | PPARAPPARDTHRBMAPTNPC1 | |
| SCHEMBL13289743 | 0.87 | THRB (0.46) | PPARATHRBMAPTNPC1HPGD | |
| SCHEMBL24293663 | 0.87 | THRB (0.40) | PPARAPPARDTHRBMAPTNPC1 | |
| SCHEMBL17229439 | 0.85 | TSHR (0.50) | PPARAPPARDTHRBMAPTNPC1 | |
| SCHEMBL32684086 | 0.85 | TSHR (0.50) | PPARAPPARDTHRBMAPTNPC1 | |
| SCHEMBL22651389 | 0.84 | THRB (0.38) | PPARAPPARDTHRBMAPTNPC1 | |
| SCHEMBL21649998 | 0.84 | THRB (0.38) | PPARAPPARDTHRBMAPTNPC1 | |
| SCHEMBL14185454 | 0.84 | THRB (0.44) | THRBMAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150315012-A1 | LIGHT DRIVEN LIQUID CRYSTAL ELASTOMER ACTUATOR | ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-11-05 | — | — | US | disclosed |