Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LGALS3 | P17931 | 4/20 | 0.34 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.34 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.34 |
| ▸ | CD69 | Q07108 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.33 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7640953 | 0.90 | KMT2A (0.43) | ALDH1A1PKMKMT2AL3MBTL1MEN1 | |
| SCHEMBL7154614 | 0.90 | KMT2A (0.43) | ALDH1A1PKMKMT2AL3MBTL1MEN1 | |
| SCHEMBL10209192 | 0.84 | ALDH1A1 (0.40) | ALDH1A1PKMKMT2AL3MBTL1THRB | |
| SCHEMBL7150056 | 0.82 | KMT2A (0.69) | ALDH1A1PKMKMT2AL3MBTL1MEN1 | |
| SCHEMBL16308901 | 0.82 | KMT2A (0.69) | ALDH1A1PKMKMT2AL3MBTL1MEN1 | |
| SCHEMBL24236918 | 0.82 | KMT2A (0.69) | ALDH1A1PKMKMT2AL3MBTL1MEN1 | |
| SCHEMBL7154807 | 0.82 | KMT2A (0.69) | ALDH1A1PKMKMT2AL3MBTL1MEN1 | |
| SCHEMBL12930889 | 0.82 | KMT2A (0.69) | ALDH1A1PKMKMT2AL3MBTL1MEN1 | |
| SCHEMBL7150336 | 0.82 | KMT2A (0.69) | ALDH1A1PKMKMT2AL3MBTL1MEN1 | |
| SCHEMBL5702889 | 0.82 | KMT2A (0.69) | ALDH1A1PKMKMT2AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015168635-A2 | COMPOSITIONS AND METHODS FOR MODULATING COMPLEMENT FACTOR B EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 2015-11-05 | — | — | WO | disclosed |