Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.55 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.55 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.50 |
| ▸ | AMD1 | P17707 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.47 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.47 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.47 |
| ▸ | GAPDH | P04406 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | STAT6 | P42226 | 1/20 | 0.47 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14928577 | 0.92 | ADORA2A (0.48) | ADORA2AADORA2BDNMT1DNMT3BEHMT1 | |
| SCHEMBL15868479 | 0.92 | ADORA2A (0.48) | ADORA2AADORA2BDNMT1DNMT3BEHMT1 | |
| SCHEMBL14946102 | 0.92 | ADORA2A (0.48) | ADORA2AADORA2BDNMT1DNMT3BEHMT1 | |
| SCHEMBL14928482 | 0.92 | ADORA2A (0.48) | ADORA2AADORA2BDNMT1DNMT3BEHMT1 | |
| SCHEMBL14946122 | 0.92 | ADORA2A (0.48) | ADORA2AADORA2BDNMT1DNMT3BEHMT1 | |
| SCHEMBL18852382 | 0.92 | ADORA2A (0.48) | ADORA2AADORA2BDNMT1DNMT3BEHMT1 | |
| SCHEMBL15868481 | 0.92 | ADORA2A (0.48) | ADORA2AADORA2BDNMT1DNMT3BEHMT1 | |
| SCHEMBL18852381 | 0.92 | ADORA2A (0.48) | ADORA2AADORA2BDNMT1DNMT3BEHMT1 | |
| SCHEMBL15868500 | 0.91 | ADORA2A (0.48) | ADORA2AADORA2BDNMT1DNMT3BEHMT1 | |
| SCHEMBL14946112 | 0.91 | ADORA2A (0.48) | ADORA2AADORA2BDNMT1DNMT3BEHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150315541-A1 | MODIFIED POLYNUCLEOTIDES FOR ALTERING CELL PHENOTYPE | MODERNATX, INC. | 2015-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150315541-A1 | MODIFIED POLYNUCLEOTIDES FOR ALTERING CELL PHENOTYPE | MSH2, POLN, PMS2 | ADORA2A 1149/4885ADORA2B 1629/4885DNMT1 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.