Sugi Predict
/ Targets
/ PMS2
Top predicted compounds (top 20 by supporting neighbours, then confidence)
| Compound | Confidence | Supporting neighbours |
|---|
Clinical trials — most relevant to PMS2 by text similarity (a relevance ranking, not an exhaustive list)
| Trial | Phase | Status |
|---|
| A Phase II Study of Tegafur-Uracil as Maintenance Chemotherapy in Patients With Stage II of Colon Cancer |
PHASE4 | UNKNOWN |
| mFOLFOX6 + Bevacizumab + PD-1 Monoclonal Antibody Vs. mFOLFOX6 in Locally Advanced pMMR/MSS CRC |
PHASE3 | RECRUITING |
| Olaparib Maintenance in Patients With MCRPC After Docetaxel Treatment Reaching Partial or Stable Response (IMANOL) |
PHASE2 | COMPLETED |
| Phase I/II Study of the Combination Immunotherapy Regimen: SX-682, TriAdeno Vaccine, Retifanlimab and IL-15 Agonist N-803 (STAR15) for Metastatic Colorectal Cancer (mCRC) |
PHASE1/PHASE2 | RECRUITING |
| Pembrolizumab, Capecitabine, and Bevacizumab for Treating Colorectal Cancer |
PHASE2 | COMPLETED |
| Real-world Trial of Individualized Precision Oncology |
PHASE2 | NOT_YET_RECRUITING |
| Study of Induction PD-1 Blockade (Nivolumab) in Patients With Surgically Complete Resectable Mismatch Repair Deficient Endometrial Cancer (NIVEC) |
PHASE2 | RECRUITING |
| Node-Sparing Low-Dose Radiotherapy Concurrent With Chemotherapy and PD-1 Inhibitor in pMMR/MSS High-Risk Locally Advanced Colon Cancer: A Prospective, Single-Arm, Phase II Trial |
PHASE2 | RECRUITING |
| Short-course Radiotherapy Followed by Sequential Chemotherapy With or Without PD-1 Monoclonal Antibody and Bevacizumab as Total Neoadjuvant Therapy in pMMR/MSS Locally Advanced Rectal Cancer （SPARK） |
PHASE2 | RECRUITING |
| Pembrolizumab Before Surgery for the Treatment of Mismatch Repair Deficient Locally Advanced Solid Cancers |
PHASE2 | COMPLETED |
| Clinical Trial of All-trans-retinoic Acid, Bevacizumab and Atezolizumab in Colorectal Cancer |
PHASE2 | ACTIVE_NOT_RECRUITING |
| Node-Sparing Short-Course Radiotherapy Plus First-Line Therapy and PD-1 Inhibitor in Unresectable/Metastastic pMMR/MSS Gastric Cancer (MODIFI-GC) |
PHASE2 | NOT_YET_RECRUITING |
| A Trial of Regorafenib Plus Lorigerlimab in Patients With Locally Recurrent or Regrowing pMMR/MSS Localized Rectal Cancer |
PHASE2 | WITHDRAWN |
| A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome |
PHASE2 | RECRUITING |
| Nodes-sparing Short-course Radiation Combined With CAPOX and Tislelizumab for MSS Middle and Low Rectal Cancer |
PHASE2 | RECRUITING |
| Avelumab in Patients With MSS, MSI-H and POLE-mutated Recurrent or Persistent Endometrial Cancer and of Avelumab/Talazoparib and Avelumab/Axitinib in Patients With MSS Recurrent or Persistent Endometrial Cancer |
PHASE2 | ACTIVE_NOT_RECRUITING |
| Naproxen in Preventing DNA Mismatch Repair Deficient Colorectal Cancer in Patients With Lynch Syndrome |
PHASE1 | COMPLETED |
| Influence of the Surgical Technique Used for Colectomies on the Concentration of Circulating Tumor DNA and the Presence of Circulating Tumor Cells: Comparison of the no Touch Technic With Either First Clamping of the Mesenteric Vessels or First Mobilization of the Tumor Followed by Clamping. |
nan | UNKNOWN |
| Pembrolizumab (MK-3475) in Patients With Recurrent Malignant Glioma With a Hypermutator Phenotype |
nan | ACTIVE_NOT_RECRUITING |
| Predictive Value of PREMM5, MMRpredict, and Universal Tumor Screening for Lynch Syndrome in Vietnam |
nan | NOT_YET_RECRUITING |
| Lynch Syndrome in Colorectal Cancer Surgery |
nan | NOT_YET_RECRUITING |
| Current Microsatellite Stability Results in Colon Cancer |
nan | NOT_YET_RECRUITING |
| The Danish Bladder Cancer Group 23 Study - A European Study on Cancer in the Upper Urinary Tract |
nan | RECRUITING |
| Faecal Microbiota Characterization in Lynch Syndrome (LS) Patients With or Without Colorectal Neoplasia |
nan | UNKNOWN |
| Small Bowel Capsule Endoscopy in Lynch Syndrome |
nan | RECRUITING |
| National Cohort of Colorectal Cancers With Microsatellite Instability |
nan | ACTIVE_NOT_RECRUITING |
| Cycling in Preventing Colorectal Cancer in Participants With Lynch Syndrome |
nan | COMPLETED |
| Cohort Evaluation of Body Fluids Early Detection of Cancer in High-risk Individuals |
nan | RECRUITING |
| Prevalence of Germline Alterations in Actionable Genes in Endometrial Cancer |
nan | NOT_YET_RECRUITING |
| Virtual Prostate Biopsy Protocol for Patients on Active Surveillance and at Risk of Prostate Cancer |
nan | WITHDRAWN |
Related proteins — ESM-2 sequence neighbours (a PMS2 binder may also engage these)