SCHEMBL17232198

SCHEMBL17232198

c1ccc(-c2cc(-c3ccccc3)nc(-c3cccc(-c4cccc5c4oc4ccccc45)c3)n2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.55
GGPS1 O95749 1/20 0.46
MAPT P10636 6/20 0.44
MEN1 O00255 5/20 0.44
KMT2A Q03164 5/20 0.44
ALDH1A1 P00352 4/20 0.44
HPGD P15428 4/20 0.44
KDM4E B2RXH2 2/20 0.44
LMNA P02545 2/20 0.44
PTGES2 Q9H7Z7 1/20 0.43
PRKDC P78527 6/20 0.41
NTSR1 P30989 1/20 0.40
PIK3CD O00329 1/20 0.39
PIK3CB P42338 1/20 0.39
ATM Q13315 1/20 0.39
GLA P06280 1/20 0.38
PRMT5 O14744 1/20 0.38
WDR77 Q9BQA1 1/20 0.38
TSHR P16473 1/20 0.38
CSF1R P07333 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14725304 0.99 ALOX5 (0.53) ALOX5GGPS1MAPTMEN1KMT2A
SCHEMBL19196635 0.99 ALOX5 (0.53) ALOX5GGPS1MAPTMEN1KMT2A
SCHEMBL18216738 0.97 ALOX5 (0.52) ALOX5GGPS1MAPTMEN1KMT2A
SCHEMBL17539804 0.96 ALOX5 (0.54) ALOX5GGPS1MAPTMEN1KMT2A
SCHEMBL16573881 0.96 ALOX5 (0.51) ALOX5GGPS1MAPTMEN1KMT2A
SCHEMBL15501660 0.96 ALOX5 (0.53) ALOX5GGPS1MAPTMEN1KMT2A
SCHEMBL17539805 0.95 ALOX5 (0.53) ALOX5GGPS1MAPTMEN1KMT2A
SCHEMBL15458355 0.95 ALOX5 (0.53) ALOX5GGPS1MAPTMEN1KMT2A
SCHEMBL15458331 0.95 ALOX5 (0.53) ALOX5GGPS1MAPTMEN1KMT2A
SCHEMBL15501915 0.95 ALOX5 (0.52) ALOX5GGPS1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3533794-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2022-02-23 EP disclosed
US-10985330-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2021-04-20 US disclosed
EP-3533794-A2 MATERIALS FOR ELECTRONIC DEVICES Merck Patent GmbH (DE) 2019-09-04 EP disclosed
US-10355223-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2019-07-16 US disclosed
EP-3137458-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-04-24 EP disclosed
US-20170062736-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2017-03-02 US disclosed
US-20170062736-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2017-03-02 US disclosed
WO-2015165563-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-11-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170062736-A1 MATERIALS FOR ELECTRONIC DEVICES EPHA3, EPHA6, DDT ALOX5 3691/4885GGPS1 2010/4885MAPT 3030/4885
US-10355223-B2 Materials for electronic devices EPHA3, EPHA6, DDT ALOX5 3691/4885GGPS1 2010/4885MAPT 3030/4885
US-10985330-B2 Materials for electronic devices EPHA3, EPHA6, DDT ALOX5 3691/4885GGPS1 2010/4885MAPT 3030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.