⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL309011 | 0.76 | — | — | |
| SCHEMBL10017208 | 0.73 | — | — | |
| SCHEMBL1934832 | 0.73 | — | — | |
| SCHEMBL6515509 | 0.73 | — | — | |
| SCHEMBL1765938 | 0.73 | — | — | |
| SCHEMBL17112672 | 0.73 | — | — | |
| SCHEMBL1762277 | 0.72 | TSHR (0.52) | — | |
| Hydrochloric Acid SCHEMBL9534244 | 0.71 | TSHR (0.50) | — | |
| SCHEMBL32688411 | 0.68 | HPGD (0.41) | — | |
| SCHEMBL313299 | 0.68 | TSHR (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188254-B2 | C-class oligonucleotide analogs with enhanced immunostimulatory potency | COLEY PHARMACEUTICAL GMBH (DE) | 2012-05-29 | — | — | US | claimed |
| EP-1728863-A2 | C-class oligonucleotide analogs with enhanced immunostimulatory potency | Coley Pharmaceutical GmbH (DE) | 2006-12-06 | — | — | EP | claimed |
| EP-1678303-A2 | C-CLASS OLIGONUCLEOTIDE ANALOGS WITH ENHANCED IMMUNOSTIMULATORY POTENCY | Coley Pharmaceutical GmbH (DE) | 2006-07-12 | — | — | EP | claimed |
| US-20050239734-A1 | C-class oligonucleotide analogs with enhanced immunostimulatory potency | COLEY PHARMACEUTICAL GMBH (DE) | 2005-10-27 | — | — | US | claimed |
| WO-2005042018-A2 | C-CLASS OLIGONUCLEOTIDE ANALOGS WITH ENHANCED IMMUNOSTIMULATORY POTENCY | COLEY PHARMACEUTICAL GMBH (DE) | 2005-05-12 | — | — | WO | claimed |
| EP-1991678-B2 | COMPOSITIONS AND METHODS FOR OLIGONUCLEOTIDE FORMULATIONS | RECHTSANWALT THOMAS BECK (DE) | 2020-07-15 | — | — | EP | disclosed |
| US-20180171338-A1 | COMPOSITIONS AND METHODS FOR OLIGONUCLEOTIDE FORMULATIONS | ADIU TIDE PHARMACEUTICALS GMBH (DE) | 2018-06-21 | — | — | US | disclosed |
| EP-1991678-B1 | COMPOSITIONS AND METHODS FOR OLIGONUCLEOTIDE FORMULATIONS | ADIUTIDE PHARMACEUTICALS GMBH (DE) | 2015-09-09 | — | — | EP | disclosed |
| EP-2405002-B1 | Compositions and methods for oligonucleotide formulations | ADIUTIDE PHARMACEUTICALS GMBH (DE) | 2014-09-24 | — | — | EP | disclosed |
| US-8188254-B2 | C-class oligonucleotide analogs with enhanced immunostimulatory potency | COLEY PHARMACEUTICAL GMBH (DE) | 2012-05-29 | — | — | US | disclosed |
| EP-2405002-A1 | Compositions and methods for oligonucleotide formulations | AdiuTide Pharmaceuticals GmbH (DE) | 2012-01-11 | — | — | EP | disclosed |
| US-20080045473-A1 | Compositions and methods for oligonucleotide formulations | COLEY PHARMACEUTICAL GMBH (DE) | 2008-02-21 | — | — | US | disclosed |
| WO-2007095316-A2 | COMPOSITIONS AND METHODS FOR OLIGONUCLEOTIDE FORMULATIONS | COLEY PHARMACEUTICAL GMBH (DE) | 2007-08-23 | — | — | WO | disclosed |
| EP-1728863-A2 | C-class oligonucleotide analogs with enhanced immunostimulatory potency | Coley Pharmaceutical GmbH (DE) | 2006-12-06 | — | — | EP | disclosed |
| EP-1678303-A2 | C-CLASS OLIGONUCLEOTIDE ANALOGS WITH ENHANCED IMMUNOSTIMULATORY POTENCY | Coley Pharmaceutical GmbH (DE) | 2006-07-12 | — | — | EP | disclosed |
| US-20050239734-A1 | C-class oligonucleotide analogs with enhanced immunostimulatory potency | COLEY PHARMACEUTICAL GMBH (DE) | 2005-10-27 | — | — | US | disclosed |
| WO-2005042018-A2 | C-CLASS OLIGONUCLEOTIDE ANALOGS WITH ENHANCED IMMUNOSTIMULATORY POTENCY | COLEY PHARMACEUTICAL GMBH (DE) | 2005-05-12 | — | — | WO | disclosed |