⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9534244 | 0.79 | TSHR (0.50) | — | |
| SCHEMBL1934832 | 0.76 | — | — | |
| SCHEMBL1765938 | 0.76 | — | — | |
| SCHEMBL9534465 | 0.76 | — | — | |
| SCHEMBL1723443 | 0.76 | — | — | |
| SCHEMBL17112672 | 0.76 | — | — | |
| SCHEMBL10402369 | 0.76 | — | — | |
| SCHEMBL10402367 | 0.76 | — | — | |
| SCHEMBL8723127 | 0.70 | — | — | |
| SCHEMBL27957615 | 0.70 | CYP3A4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100242188-A1 | COMPOSITION FOR COLOURING KERATINOUS MATERIAL USING A SUPRA-MOLECULAR COLOURING SYSTEM | L'OREAL S.A. (FR) | 2010-09-30 | — | — | US | claimed |
| CN-114384756-A | Resin composition, toner for developing electrostatic image, image forming method, photosensitive adhesive, and photoswitch material | 柯尼卡美能达株式会社 | 2022-04-22 | — | — | CN | disclosed |
| EP-2035419-B1 | 5-ARYL-SUBSTITUTED DIHYDROPYRIDOPYRIMIDINES AND DIHYDROPYRIDAZINES AND USE THEREOF AS MINERAL CORTICOID ANTAGONISTS | BAYER IP GMBH (DE) | 2016-06-22 | — | — | EP | disclosed |
| US-8399471-B2 | Aryl-or heteroaryl-substituted pyrido[2,3-d] pyrimidines and pharmaceutical compositions of the same | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-03-19 | — | — | US | disclosed |
| US-8399471-B2 | Aryl-or heteroaryl-substituted pyrido[2,3-d] pyrimidines and pharmaceutical compositions of the same | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-03-19 | — | — | US | disclosed |
| US-8093380-B2 | Viricides, antitumor agents, anticancer agents | PHARMASSET, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-20100242188-A1 | COMPOSITION FOR COLOURING KERATINOUS MATERIAL USING A SUPRA-MOLECULAR COLOURING SYSTEM | L'OREAL S.A. (FR) | 2010-09-30 | — | — | US | disclosed |
| US-20100035902-A1 | 5-ARYL-SUBSTITUTED DIHYDROPYRIDOPYRIMIDINES AND DIHYDROPYRIDAZINES AND USE THEREOF AS MINERAL CORTICOID ANTAGONISTS | BAYER HEALTHCARE AG (DE) | 2010-02-11 | — | — | US | disclosed |
| US-20100035902-A1 | 5-ARYL-SUBSTITUTED DIHYDROPYRIDOPYRIMIDINES AND DIHYDROPYRIDAZINES AND USE THEREOF AS MINERAL CORTICOID ANTAGONISTS | BAYER HEALTHCARE AG (DE) | 2010-02-11 | — | — | US | disclosed |
| EP-1545545-A4 | COMPOUNDS WITH THE BICYCLO 4.2.1 NONANE SYSTEM FOR THE TREATMENT OF i FLAVIVIRIDAE /i INFECTIONS | PHARMASSET INC (US) | 2008-09-03 | — | — | EP | disclosed |
| US-20040082574-A1 | Compounds with the bicyclo[4.2.1]nonane system for the treatment of flavivridae infections | PHARMASSET, INC. | 2004-04-29 | — | — | US | disclosed |
| WO-2004013300-A2 | COMPOUNDS WITH THE BICYCLO[4.2.1]NONANE SYSTEM FOR THE TREATMENT OF FLAVIVIRIDAE INFECTIONS | PHARMASSET INC. (US) | 2004-02-12 | — | — | WO | disclosed |
| US-6683166-B2 | RESISTANT TO NUCLEASES, ENHANCED ABILITY TO PENETRATE CELLS, AND CAPABLE OF BINDING TARGET OLIGONUCLEOTIDE SEQUENCES IN VITRO AND VIVO | ISIS PHARMACEUTICALS, INC. | 2004-01-27 | — | — | US | disclosed |
| WO-2003089895-A2 | METHODS FOR THE ELECTROCHEMICAL DETECTION OF MULTIPLE TARGET COMPOUNDS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2003-10-30 | — | — | WO | disclosed |
| US-20030152960-A1 | Methods for the electrochemical detection of multiple target compounds | ROCHE MOLECULAR SYSTEMS, INC. | 2003-08-14 | — | — | US | disclosed |
| US-20030120050-A1 | Modified internucleoside linkages (ii) | SWAMINATHAN SUNDARAMOORTHI (US) | 2003-06-26 | — | — | US | disclosed |
| US-6410702-B1 | OLIGONUCLEOTIDE; FOR USE IN THE HUMAN THERAPEUTICS AND DIAGNOSTICS | ISIS PHARMACEUTICALS, INC. | 2002-06-25 | — | — | US | disclosed |
| US-5817781-A | ENZYME INHIBITORS; INCREASED PENETRATION OF CELLS; DEACTIVATEPROTEIN SYNTHESIS, RNA, DNA | GILEAD SCIENCES, INC. (US) | 1998-10-06 | — | — | US | disclosed |
| US-5106951-A | Antineoplastic anthracyline agents intercalated with two aromatic side chains or an oligopeptide and covalently attached to an antibody | NEORX CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0329184-A2 | Antimers and antimeric conjugation | NEORX CORPORATION (US) | 1989-08-23 | — | — | EP | disclosed |