Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 4/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.70 |
| ▸ | SRC | P12931 | 2/20 | 0.70 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.70 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.70 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.70 |
| ▸ | LDHA | P00338 | 1/20 | 0.70 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.70 |
| ▸ | FBP1 | P09467 | 1/20 | 0.70 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.70 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.70 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.70 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.70 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.70 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.70 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3699269 | 0.91 | P2RY1 (0.68) | P2RY1ADORA1SMN1; SMN2P2RY2SRC | |
| SCHEMBL1000175 | 0.91 | P2RY1 (0.68) | P2RY1ADORA1SMN1; SMN2P2RY2SRC | |
| SCHEMBL6569310 | 0.89 | ADORA1 (0.73) | P2RY1ADORA1SMN1; SMN2P2RY2SRC | |
| SCHEMBL4356493 | 0.89 | P2RY1 (0.66) | P2RY1ADORA1SMN1; SMN2P2RY2SRC | |
| SCHEMBL381173 | 0.89 | P2RY1 (0.66) | P2RY1ADORA1SMN1; SMN2P2RY2SRC | |
| SCHEMBL8708990 | 0.88 | ADORA1 (0.71) | P2RY1ADORA1SMN1; SMN2P2RY2SRC | |
| SCHEMBL939593 | 0.88 | ADORA1 (0.71) | P2RY1ADORA1SMN1; SMN2P2RY2SRC | |
| SCHEMBL28978257 | 0.88 | P2RY1 (0.65) | P2RY1ADORA1SMN1; SMN2P2RY2SRC | |
| SCHEMBL1757017 | 0.87 | ADORA1 (0.73) | P2RY1ADORA1SMN1; SMN2P2RY2SRC | |
| SCHEMBL19859780 | 0.87 | ADORA1 (0.73) | P2RY1ADORA1SMN1; SMN2P2RY2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1743940-B1 | CARDIOINHIBITORY/ ANTIHYPERTENSIVE NOVEL ENDOGENOUS PHYSIOLOGICALLY ACTIVE PEPTIDE | JAPAN SCIENCE & TECH AGENCY (JP) | 2012-01-18 | — | — | EP | disclosed |
| US-7829526-B2 | Cardioinhibitory/antihypertensive novel endogenous physiologically active peptide | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-11-09 | — | — | US | disclosed |
| US-20080267871-A1 | Cardioinhibitory/ Antihypertensive Novel Endogenous Physiologically Active Peptide | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-10-30 | — | — | US | disclosed |
| EP-1743940-A1 | CARDIOINHIBITORY/ ANTIHYPERTENSIVE NOVEL ENDOGENOUS PHYSIOLOGICALLY ACTIVE PEPTIDE | Japan Science and Technology Agency (JP) | 2007-01-17 | — | — | EP | disclosed |