Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13995706 | 0.86 | TAAR1 (0.42) | TAAR1KMT2AMEN1TDP1NPC1 | |
| SCHEMBL10203575 | 0.82 | MEN1 (0.36) | TAAR1KMT2AMEN1TDP1KDM4E | |
| SCHEMBL10746076 | 0.79 | ALDH1A1 (0.49) | TAAR1KMT2ATDP1NPC1RAB9A | |
| SCHEMBL31558942 | 0.77 | CHRM2 (0.56) | TAAR1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL23374589 | 0.77 | CHRM2 (0.56) | TAAR1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL11879864 | 0.76 | CHRM2 (0.48) | TAAR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL11235509 | 0.74 | TAAR1 (0.58) | TAAR1TDP1NPC1RAB9AALDH1A1 | |
| SCHEMBL13948898 | 0.74 | TAAR1 (0.52) | TAAR1TDP1NPC1RAB9AKDM4E | |
| SCHEMBL5026910 | 0.74 | TAAR1 (0.52) | TAAR1TDP1NPC1RAB9AKDM4E | |
| SCHEMBL11922803 | 0.73 | CHRM2 (0.47) | TAAR1KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |