⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL606391 | 1.00 | — | — | |
| SCHEMBL7496575 | 1.00 | — | — | |
| SCHEMBL1726593 | 1.00 | — | — | |
| SCHEMBL7496569 | 1.00 | — | — | |
| SCHEMBL64396 | 1.00 | — | — | |
| SCHEMBL1724943 | 1.00 | — | — | |
| SCHEMBL606385 | 1.00 | — | — | |
| SCHEMBL29208889 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL3332500 | 0.98 | CCR5 (0.36) | — | |
| SCHEMBL8704625 | 0.93 | EPAS1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112010851-A | Preparation method of moxifloxacin hydrochloride | 浙江美诺华药物化学有限公司 | 2020-12-01 | — | — | CN | claimed |
| EP-2403831-B1 | SYNTHESIS OF (4aS,7aS)-OCTAHYDRO-1H-PYRROLOÝ3,4-b¨PYRIDINE | ITALIANA SINT SPA (IT) | 2015-05-20 | — | — | EP | claimed |
| US-20110137036-A1 | SYNTHESIS OF (4aS,7aS)-OCTAHYDRO-1H-PYRROLO[3,4-b]PYRIDINE | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A (IT) | 2011-06-09 | — | — | US | claimed |
| CN-118147101-A | Method for preparing moxifloxacin intermediate by enzyme catalysis | 湖州颐盛生物科技有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-111024831-B | Method for separating moxifloxacin hydrochloride and impurities thereof by high performance liquid chromatography | 江苏正大丰海制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110746334-B | Method for preparing 3- (3-chloropropyl) -4-oxopyrrolidine-1-carboxylic ester | 上海朴颐化学科技有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-112010851-A | Preparation method of moxifloxacin hydrochloride | 浙江美诺华药物化学有限公司 | 2020-12-01 | — | — | CN | disclosed |
| CN-112010851-A | Preparation method of moxifloxacin hydrochloride | 浙江美诺华药物化学有限公司 | 2020-12-01 | — | — | CN | disclosed |
| CN-111024831-A | Method for separating moxifloxacin hydrochloride and impurities thereof by high performance liquid chromatography | 江苏正大丰海制药有限公司 | 2020-04-17 | — | — | CN | disclosed |
| EP-2403831-B1 | SYNTHESIS OF (4aS,7aS)-OCTAHYDRO-1H-PYRROLOÝ3,4-b¨PYRIDINE | ITALIANA SINT SPA (IT) | 2015-05-20 | — | — | EP | disclosed |
| CN-102964346-B | Preparation method of (S, S)-octahydro-6H-pyrrolo[3, 4-b]pyridine | SINOCHEM CORP | 2015-04-22 | — | — | CN | disclosed |
| US-8680276-B2 | Synthesis of (4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridine | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A (IT) | 2014-03-25 | — | — | US | disclosed |
| EP-2599386-A1 | 2-aminopyrimidine modulators of the histamine h4 receptor | Janssen Pharmaceutica N.V. (BE) | 2013-06-05 | — | — | EP | disclosed |
| CN-102964346-A | Preparation method of (S, S)-octahydro-6H-pyrrolo[3, 4-b]pyridine | SINOCHEM CORP | 2013-03-13 | — | — | CN | disclosed |
| CN-102964346-A | Preparation method of (S, S)-octahydro-6H-pyrrolo[3, 4-b]pyridine | SINOCHEM CORP | 2013-03-13 | — | — | CN | disclosed |
| EP-2403831-A1 | SYNTHESIS OF (4aS,7aS)-OCTAHYDRO-1H-PYRROLOÝ3,4-b¨PYRIDINE | F.I.S. Fabbrica Italiana Sintetici S.p.A. (IT) | 2012-01-11 | — | — | EP | disclosed |
| US-20110137036-A1 | SYNTHESIS OF (4aS,7aS)-OCTAHYDRO-1H-PYRROLO[3,4-b]PYRIDINE | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A (IT) | 2011-06-09 | — | — | US | disclosed |
| US-20110137036-A1 | SYNTHESIS OF (4aS,7aS)-OCTAHYDRO-1H-PYRROLO[3,4-b]PYRIDINE | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A (IT) | 2011-06-09 | — | — | US | disclosed |
| WO-2010100215-A1 | SYNTHESIS OF (4aS,7aS)-OCTAHYDRO-1H-PYRROLO[3,4-b]PYRIDINE | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2010-09-10 | — | — | WO | disclosed |
| US-20080306105-A1 | DEUTERIUM-ENRICHED MOXIFLOXACIN | PROTIA, LLC (US) | 2008-12-11 | — | — | US | disclosed |