Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 18/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17237480 | 0.88 | CRHR1 (0.66) | CRHR1 | |
| SCHEMBL7678011 | 0.85 | CRHR1 (0.81) | CRHR1 | |
| SCHEMBL7678068 | 0.81 | CRHR1 (0.61) | CRHR1 | |
| SCHEMBL7684970 | 0.81 | CRHR1 (0.65) | CRHR1 | |
| SCHEMBL7687291 | 0.81 | CRHR1 (0.63) | CRHR1 | |
| SCHEMBL7680583 | 0.81 | CRHR1 (0.56) | CRHR1 | |
| Hydrochloric Acid SCHEMBL17237479 | 0.80 | CRHR1 (0.61) | CRHR1 | |
| SCHEMBL7681029 | 0.80 | CRHR1 (0.68) | CRHR1 | |
| SCHEMBL7680614 | 0.76 | CRHR1 (0.73) | CRHR1 | |
| SCHEMBL7680751 | 0.76 | CRHR1 (0.70) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282607-B1 | PRODRUGS OF HIV REPLICATION INHIBITING PYRIMIDINES | JANSSEN PHARMACEUTICA NV (BE) | 2015-11-11 | — | — | EP | claimed |