Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 11/20 | 0.65 |
| ▸ | F2 | P00734 | 5/20 | 0.36 |
| ▸ | F10 | P00742 | 5/20 | 0.36 |
| ▸ | PLAU | P00749 | 3/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | HPN | P05981 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1950271 | 0.88 | F9 (0.66) | F9F2F10PLAUPLG | |
| SCHEMBL17237632 | 0.85 | F9 (0.74) | F9F2F10PLAUPLG | |
| SCHEMBL1439830 | 0.84 | F9 (0.65) | F9F2F10PLAUPLG | |
| SCHEMBL1948013 | 0.84 | F9 (0.65) | F9F2F10PLAUPLG | |
| SCHEMBL1950646 | 0.83 | F9 (0.64) | F9F2F10PLAUPLG | |
| SCHEMBL17237649 | 0.83 | F9 (0.74) | F9F2F10ITGB3ITGA2B | |
| SCHEMBL7901577 | 0.83 | F9 (0.70) | F9F2F10PLAUPLG | |
| SCHEMBL17237652 | 0.82 | F9 (0.79) | F9F2 | |
| SCHEMBL17237646 | 0.82 | F9 (0.70) | F9F2F10PLAUHPN | |
| SCHEMBL1947607 | 0.82 | F9 (0.60) | F9F2F10ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373634-B1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARM CO LTD (JP) | 2015-11-11 | — | — | EP | disclosed |