Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 11/20 | 0.70 |
| ▸ | F2 | P00734 | 6/20 | 0.45 |
| ▸ | F10 | P00742 | 3/20 | 0.45 |
| ▸ | PLAU | P00749 | 3/20 | 0.45 |
| ▸ | PLG | P00747 | 2/20 | 0.45 |
| ▸ | PLAT | P00750 | 2/20 | 0.45 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | HPN | P05981 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1948970 | 0.91 | F9 (0.68) | F9F2F10PLAUPLG | |
| SCHEMBL12545890 | 0.88 | F9 (0.82) | F9F2F10PLAUPLG | |
| SCHEMBL1947953 | 0.88 | F9 (0.68) | F9F2F10KLK1KLK5 | |
| SCHEMBL1950503 | 0.88 | F9 (0.67) | F9F2F10PLAUPLG | |
| SCHEMBL17237641 | 0.88 | F9 (0.68) | F9F2F10PLAUPLG | |
| SCHEMBL12547899 | 0.88 | F9 (0.67) | F9F2F10PLAUPLG | |
| SCHEMBL17237644 | 0.87 | F9 (0.67) | F9F2F10PLAUPLG | |
| SCHEMBL1947490 | 0.87 | F9 (0.63) | F9F2F10PLAUPLG | |
| SCHEMBL1948534 | 0.87 | F9 (0.66) | F9F2F10PLAUPLG | |
| SCHEMBL1947068 | 0.86 | F9 (0.62) | F9F2F10KLK1KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065717-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |