SCHEMBL1723919

SCHEMBL1723919

CC1CC1(C)C(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28437217 1.00
SCHEMBL5314812 1.00
Hydrochloric Acid SCHEMBL4621231 0.97
SCHEMBL27633258 0.78
SCHEMBL4194876 0.77
SCHEMBL25330082 0.77
SCHEMBL19557132 0.77
SCHEMBL17479965 0.77
SCHEMBL5314714 0.77
SCHEMBL3129970 0.77 APLNR (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12247036-B2 Tricyclic compounds for the treatment of cancer HOFFMANN-LA ROCHE INC. (US) 2025-03-11 US claimed
US-20240417410-A1 TRICYCLIC COMPOUNDS FOR THE TREATMENT OF CANCER HOFFMANN-LA ROCHE INC. (US) 2024-12-19 US claimed
CN-107207472-B Inhibitors of AKT kinase 卑尔根生物股份公司 2020-08-14 CN claimed
CN-109286041-A Electrolyte and secondary lithium battery 宁德时代新能源科技股份有限公司 2019-01-29 CN claimed
EP-3240784-A2 INHIBITORS OF AKT KINASE BerGenBio ASA (NO) 2017-11-08 EP claimed
CN-104193645-B Preparation method of chiral dimethyl cyclopropyl carboxamide 上海应用技术学院 2017-02-01 CN claimed
WO-2016102672-A2 PHARMACEUTICALLY ACTIVE COMPOUNDS BERGENBIO AS (NO) 2016-06-30 WO claimed
EP-2699547-B1 5-(PHENYL/PYRIDINYL-ETHINYL)-2-PYRIDINE/2-PYRIMIDINE-CARBORXAMIDES AS MGLUR5 MODULATORS HOFFMANN LA ROCHE (CH) 2015-03-04 EP claimed
CN-104193645-A Preparation method of chiral dimethyl cyclopropyl carboxamide SHANGHAI INST TECHNOLOGY 2014-12-10 CN claimed
US-8906930-B2 Quinazoline derivatives MERCK PATENT GMBH (DE) 2014-12-09 US claimed
EP-2504314-A1 QUINAZOLINE DERIVATIVES Merck Patent GmbH (DE) 2012-10-03 EP claimed
US-20120238582-A1 QUINAZOLINE DERIVATIVES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-09-20 US claimed
WO-2011061609-A2 PROCESSES FOR THE PREPARATION OF CILASTATIN RANBAXY LABORATORIES LIMITED (IN) 2011-05-26 WO claimed
WO-2011060873-A1 QUINAZOLINE DERIVATIVES MERCK PATENT GMBH (DE) 2011-05-26 WO claimed
CN-1824795-A Optical selective screening process for amidase UNIV ZHEJIANG POLYTECHNIC (CN) 2006-08-30 CN claimed
JP-5076391-A None JP disclosed
JP-5236993-A None JP disclosed
JP-H05236993-A GENETIC ENGINEERING PRODUCTION OF S-(+)-2,2-DIMETHYLCYCLOPROPANECARBOXAMIDE BY MICROORGANISM LONZA AG 1993-09-17 JP disclosed
JP-H0576391-A BIOTECHNOLOGICAL PRODUCTION OF S-(+)-2, 2-DTMETHYLCYCLOPROPANECARBOXAMIDE LONZA AG 1993-03-30 JP disclosed
US-4288621-A Substituted 2,2-dimethylcyclopropaneamides ZOECON CORPORATION (US) 1981-09-08 US disclosed