Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 10/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 3/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15000235 | 0.93 | RAB9A (0.41) | KDM4EMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL286605 | 0.92 | MAPT (0.37) | KDM4EMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL14331284 | 0.86 | KDM4E (0.39) | PDE10AKDM4EMAPTRAB9ALGALS3 | |
| SCHEMBL13080993 | 0.81 | KDM4E (0.34) | PDE10AKDM4EMAPTRAB9ANPC1 | |
| SCHEMBL14407267 | 0.81 | KDM4E (0.34) | PDE10AKDM4EMAPTRAB9ANPC1 | |
| SCHEMBL15000232 | 0.80 | RAB9A (0.40) | PDE10AKDM4EMAPTRAB9ANPC1 | |
| SCHEMBL286507 | 0.79 | KDM4E (0.39) | PDE10AKDM4EMAPTRAB9ANPC1 | |
| SCHEMBL15000242 | 0.78 | KDM4E (0.47) | KDM4EMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL297504 | 0.77 | KDM4E (0.43) | KDM4EMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL286745 | 0.75 | SYK (0.38) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150322069-A1 | PHENOXYMETHYL HETEROCYCLIC COMPOUNDS | FMR LLC | 2015-11-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322069-A1 | PHENOXYMETHYL HETEROCYCLIC COMPOUNDS | PDE3A, PDE2A, PDE5A | PDE10A 7/4885KDM4E 559/4885MAPT 1299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.