Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18844962 | 1.00 | EPHX1 (0.42) | EPHX1SMN1; SMN2SHBGCYP2D6GAA | |
| SCHEMBL7776737 | 1.00 | EPHX1 (0.42) | EPHX1SMN1; SMN2SHBGCYP2D6GAA | |
| SCHEMBL6061582 | 1.00 | EPHX1 (0.42) | EPHX1SMN1; SMN2SHBGCYP2D6GAA | |
| SCHEMBL7770562 | 0.98 | EPHX1 (0.39) | EPHX1SMN1; SMN2SHBGCYP2D6GAA | |
| SCHEMBL2411184 | 0.89 | — | — | |
| SCHEMBL11057849 | 0.88 | SIGMAR1 (0.40) | EPHX1SHBGEPHX2MEN1KMT2A | |
| SCHEMBL25476883 | 0.86 | EPHX1 (0.40) | EPHX1SMN1; SMN2SHBGGAAL3MBTL1 | |
| SCHEMBL11057091 | 0.86 | EPHX1 (0.41) | EPHX1EPHX2MEN1KMT2A | |
| SCHEMBL19593153 | 0.86 | EPHX1 (0.41) | EPHX1EPHX2MEN1KMT2A | |
| SCHEMBL18520361 | 0.84 | SIGMAR1 (0.44) | EPHX1ALDH1A1EPHX2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |