Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL742272 | 0.87 | RAB9A (0.75) | RAB9AALDH1A1TDP1ROCK2KDM4E | |
| SCHEMBL6455377 | 0.86 | RAB9A (0.74) | RAB9AALDH1A1TDP1ROCK2KDM4E | |
| SCHEMBL4165132 | 0.86 | RAB9A (0.74) | RAB9AALDH1A1TDP1ROCK2KDM4E | |
| SCHEMBL28662140 | 0.86 | RAB9A (1.00) | RAB9AALDH1A1TDP1ROCK2KDM4E | |
| Hydrochloric Acid SCHEMBL6831509 | 0.86 | RAB9A (0.73) | RAB9AALDH1A1TDP1ROCK2KDM4E | |
| SCHEMBL6120093 | 0.85 | RAB9A (0.72) | RAB9AALDH1A1TDP1ROCK2KDM4E | |
| SCHEMBL3692391 | 0.84 | RAB9A (0.67) | RAB9AALDH1A1ROCK2KDM4E | |
| SCHEMBL30678410 | 0.84 | RAB9A (0.70) | RAB9AALDH1A1TDP1ROCK2KDM4E | |
| SCHEMBL3699763 | 0.84 | RAB9A (0.70) | RAB9AALDH1A1TDP1ROCK2KDM4E | |
| SCHEMBL620646 | 0.84 | TDP1 (0.76) | RAB9AALDH1A1TDP1MEN1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085482-B | Substituted diethylenediamine compound and its application method and purposes | 广东东阳光药业有限公司 | 2018-08-10 | — | — | CN | disclosed |
| WO-2015169180-A1 | SUBSTITUTED PIPERAZINE COMPOUNDS AND METHODS AND USE THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-11-12 | — | — | WO | disclosed |