SCHEMBL17242

SCHEMBL17242

O=S(=O)(Cl)c1ccc(F)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.55
HSD17B10 Q99714 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
MMP2 P08253 2/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
MMP1 P03956 1/20 0.50
MMP9 P14780 1/20 0.50
MMP8 P22894 1/20 0.50
MMP13 P45452 1/20 0.50
SOS1 Q07889 1/20 0.45
F2 P00734 1/20 0.45
PRSS1 P07477 1/20 0.45
PRSS2 P07478 1/20 0.45
PRSS3 P35030 1/20 0.45
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
PKM P14618 1/20 0.43
PTGS2 P35354 3/20 0.42
MAOA P21397 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38661446 1.00 ALDH1A1 (0.55) ALDH1A1HSD17B10TDP1MMP2CA1
Ammonia Solution, Strong SCHEMBL28862290 0.97 ALDH1A1 (0.52) ALDH1A1HSD17B10TDP1MMP2CA1
SCHEMBL995471 0.93 ALDH1A1 (0.48) ALDH1A1HSD17B10TDP1MMP2CA1
SCHEMBL8589523 0.91 ALDH1A1 (0.52) ALDH1A1HSD17B10TDP1CA1CA2
SCHEMBL282256 0.87 SOS1 (0.66) ALDH1A1HSD17B10TDP1MMP2CA1
SCHEMBL13297336 0.87 HTR2A (0.45) ALDH1A1HSD17B10TDP1MMP2MMP1
SCHEMBL651902 0.85 ALDH1A1 (0.71) ALDH1A1HSD17B10TDP1MMP2CA1
SCHEMBL14401901 0.85 ALDH1A1 (0.41) ALDH1A1HSD17B10TDP1MMP2CA1
SCHEMBL7534260 0.83 HTR2A (0.50) ALDH1A1HSD17B10TDP1CA1CA2
Fluorobenzene SCHEMBL7167290 0.82 ALDH1A1 (0.76) ALDH1A1HSD17B10TDP1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5388 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117865932-B Preparation method of benzothiophene sulfone compound with medicinal and fluorescent activity BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY (CN) 2026-05-26 CN claimed
CN-117126138-B Compound for degrading target protein in ubiquitin-proteasome system, and preparation method and application thereof 深圳湾实验室坪山生物医药研发转化中心 2026-05-22 CN claimed
EP-4692062-A1 NOVEL AMIDE-BASED COMPOUND AND COMPOSITION COMPRISING SAME Amorepacific Corporation (KR) 2026-02-11 EP claimed
CN-119864499-A Composite solid polymer electrolyte material of lithium ion battery and preparation method thereof 贵州师范大学 2025-04-22 CN claimed
CN-119490439-A Preparation method of arylsulfonyl amino quaternary ammonium salt antibacterial agent 苏州华道生物药业股份有限公司 2025-02-21 CN claimed
CN-119481584-A High-flame-retardance lithium ion battery multilayer diaphragm and preparation method and application thereof 重庆厚生新材料科技有限公司 2025-02-18 CN claimed
CN-119425423-A Positively charged composite membrane and preparation method and application thereof 中国石油化工股份有限公司 2025-02-14 CN claimed
CN-119414012-A Nanometer magnetic bead for cell sorting and preparation method thereof 浙江理工大学绍兴生物医药研究院有限公司 2025-02-11 CN claimed
US-12162883-B2 Process for the preparation of intermediates useful for making (2S,5R)-7-oxo-n-piperidin-4-yl-6-(sulfoxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide MERCK SHARP & DOHME LLC (US) 2024-12-10 US claimed
US-20240368063-A1 PREPARATION METHOD, INTERMEDIATE COMPOUNDS, AND SYNTHESIS METHOD FOR A CLASS OF ANTHRACENE-DERIVED TOXINS IN ORGANIC CHEMISTRY WUYAN PHARMACEUTICAL TECHNOLOGY (SHANGHAI) CO., LTD (CN) 2024-11-07 US claimed
US-5204451-A ACTIVATING HYDROXYL GROUPS OF POLYMERIC CARRIERS USING 4-FLUOROBENZENESULFONYL CHLORIDE FOR BINDING BIOLOGICALLY ACTIVE LIGANDS BAXTER INTERNATIONAL INC. (US) 1993-04-20 US claimed
EP-0288268-B1 4-DEMETHOXY-4-AMINO-ANTHRACYCLINES FARMITALIA CARLO ERBA S.r.l. (IT) 1992-12-09 EP claimed
EP-0502140-A1 ACTIVATING HYDROXYL GROUPS OF POLYMERIC CARRIERS USING 4-FLUOROBENZENESULFONYL CHLORIDE BAXTER INTERNATIONAL INC. (US) 1992-09-09 EP claimed
WO-1992003544-A1 ACTIVATING HYDROXYL GROUPS OF POLYMERIC CARRIERS USING 4-FLUOROBENZENESULFONYL CHLORIDE BAXTER INTERNATIONAL INC. (US) 1992-03-05 WO claimed
US-5081306-A Synthesis of dihalobenzene disulfone compounds AMOCO CORPORATION (US) 1992-01-14 US claimed
US-5015745-A Ketalization, sulfonylation, amination and diazotization to form a demethoxydaunomycinone FARMITALIA CARLO ERBA S.R.L. (IT) 1991-05-14 US claimed
US-4965351-A INTERMEDIATES FOR ANTITUMOR AGENTS FARMITALIA CARLO ERBA S.R.L. (IT) 1990-10-23 US claimed
EP-0328399-A2 Process for the preparation of 4-demethoxydaunomycinone, the aglycone of 4-demethoxy-daunorubicin FARMITALIA CARLO ERBA S.r.l. (IT) 1989-08-16 EP claimed
EP-0288268-A2 4-Demethoxy-4-amino-anthracyclines FARMITALIA CARLO ERBA S.r.l. (IT) 1988-10-26 EP claimed
US-4187225-A Novel synthesis of bis pyrazolone oxonol dyes POLAROID CORPORATION (US) 1980-02-05 US claimed