SCHEMBL17243446

SCHEMBL17243446

CC1(C)c2ccccc2-c2ccc(-c3ccc(N(c4ccccc4)c4ccc5c(c4)C(C)(C)c4cc(-c6ccc7ccccc7c6)ccc4-5)cc3)cc21

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 12/20 0.37
LPL P06858 1/20 0.37
LIPG Q9Y5X9 1/20 0.37
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
ACMSD Q8TDX5 1/20 0.33
GSTP1 P09211 1/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17243506 1.00 PDK2 (0.37) PDK2LPLLIPGESR1ESR2
SCHEMBL17243528 1.00 PDK2 (0.37) PDK2LPLLIPGESR1ESR2
SCHEMBL21968964 0.99 PDK2 (0.39) PDK2LPLLIPGESR1ESR2
SCHEMBL24255786 0.99 LPL (0.38) PDK2LPLLIPGESR1ESR2
SCHEMBL17243435 0.99 PDK2 (0.37) PDK2LPLLIPGESR1ESR2
SCHEMBL10034406 0.97 PDK2 (0.40) PDK2LPLLIPGESR1ESR2
SCHEMBL16366430 0.97 PDK2 (0.40) PDK2LPLLIPGESR1ESR2
SCHEMBL23950945 0.97 PDK2 (0.40) PDK2LPLLIPGESR1ESR2
SCHEMBL17153662 0.97 PDK2 (0.40) PDK2LPLLIPGESR1ESR2
SCHEMBL17153730 0.97 PDK2 (0.40) PDK2LPLLIPGESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9184395-B2 Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2015-11-10 US disclosed
US-9184395-B2 Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2015-11-10 US disclosed