Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 7/20 | 0.65 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.64 |
| ▸ | ACE | P12821 | 2/20 | 0.61 |
| ▸ | MMP2 | P08253 | 3/20 | 0.61 |
| ▸ | MMP8 | P22894 | 3/20 | 0.61 |
| ▸ | MMP1 | P03956 | 2/20 | 0.61 |
| ▸ | MMP7 | P09237 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | IL1RN | P18510 | 1/20 | 0.57 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30496933 | 1.00 | ECE1 (0.65) | ECE1ERAP2ACEMMP2MMP8 | |
| SCHEMBL29640305 | 1.00 | ECE1 (0.65) | ECE1ERAP2ACEMMP2MMP8 | |
| SCHEMBL29640357 | 1.00 | ECE1 (0.65) | ECE1ERAP2ACEMMP2MMP8 | |
| SCHEMBL30496932 | 1.00 | ECE1 (0.65) | ECE1ERAP2ACEMMP2MMP8 | |
| SCHEMBL15648656 | 0.93 | ECE1 (0.71) | ECE1ERAP2ACEIL1RNERAP1 | |
| SCHEMBL28478871 | 0.93 | ACE (0.64) | ECE1ACEMMP2MMP8MMP9 | |
| SCHEMBL15692405 | 0.93 | ECE1 (0.71) | ECE1ERAP2ACEIL1RNERAP1 | |
| SCHEMBL28518121 | 0.92 | MMP2 (0.59) | ECE1ERAP2MMP2MMP8MMP1 | |
| SCHEMBL28518120 | 0.92 | MMP2 (0.59) | ECE1ERAP2MMP2MMP8MMP1 | |
| SCHEMBL25264480 | 0.91 | MEN1 (0.64) | ACEPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9180201-B2 | Method for preparing lipopeptide compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-11-10 | — | — | US | disclosed |