Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7944594 | 0.80 | TAAR1 (0.66) | TAAR1CYP2D6 | |
| SCHEMBL1834714 | 0.80 | TAAR1 (0.66) | TAAR1CYP2D6 | |
| SCHEMBL18331177 | 0.68 | TAAR1 (0.46) | TAAR1CYP2D6 | |
| SCHEMBL13907974 | 0.67 | SIGMAR1 (0.44) | TAAR1CYP2D6 | |
| SCHEMBL1837662 | 0.65 | TAAR1 (0.64) | TAAR1CYP2D6 | |
| SCHEMBL19407408 | 0.63 | TAAR1 (0.52) | TAAR1CYP2D6 | |
| SCHEMBL4785594 | 0.61 | SIGMAR1 (0.64) | TAAR1CYP2D6 | |
| SCHEMBL3611960 | 0.61 | TAAR1 (0.55) | TAAR1 | |
| SCHEMBL19407475 | 0.61 | TAAR1 (0.56) | TAAR1 | |
| SCHEMBL3610278 | 0.61 | TAAR1 (1.00) | TAAR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321287-B1 | 4,5-DIHYDRO-OXAZOL-2-YL DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2015-11-11 | — | — | EP | disclosed |