Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.67 |
| ▸ | ANPEP | P15144 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.56 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | SCN4A | P35499 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14471186 | 1.00 | EPHX1 (0.67) | EPHX1ANPEPSIGMAR1SLC6A2TAAR1 | |
| SCHEMBL3401432 | 1.00 | EPHX1 (0.67) | EPHX1ANPEPSIGMAR1SLC6A2TAAR1 | |
| Hydrochloric Acid SCHEMBL6659825 | 0.98 | EPHX1 (0.64) | EPHX1ANPEPSIGMAR1SLC6A2TAAR1 | |
| Bromide SCHEMBL6947335 | 0.98 | EPHX1 (0.64) | EPHX1ANPEPSIGMAR1SLC6A2TAAR1 | |
| SCHEMBL2736211 | 0.96 | EPHX1 (0.61) | EPHX1ANPEPSIGMAR1SLC6A2TAAR1 | |
| Bicarbonate SCHEMBL3217828 | 0.89 | EPHX1 (0.53) | EPHX1ANPEPSIGMAR1SLC6A2TAAR1 | |
| SCHEMBL9468396 | 0.88 | EPHX1 (0.52) | EPHX1ANPEPSIGMAR1SLC6A2TAAR1 | |
| SCHEMBL21469786 | 0.88 | EPHX1 (0.61) | EPHX1ANPEPSIGMAR1SLC6A2TAAR1 | |
| SCHEMBL3847568 | 0.88 | EPHX1 (0.61) | EPHX1ANPEPSIGMAR1SLC6A2TAAR1 | |
| Hydrochloric Acid SCHEMBL9468395 | 0.87 | EPHX1 (0.50) | EPHX1ANPEPSIGMAR1SLC6A2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |