SCHEMBL9468396

SCHEMBL9468396

CCCC(N)Cc1ccc(-c2ccccc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.52
SIGMAR1 Q99720 3/20 0.48
ANPEP P15144 1/20 0.46
TAAR1 Q96RJ0 4/20 0.45
CSNK1E P49674 1/20 0.45
SLC6A2 P23975 2/20 0.44
MAOA P21397 1/20 0.44
SLC6A4 P31645 1/20 0.44
SLC6A3 Q01959 1/20 0.44
CYP2A6 P11509 1/20 0.44
ADORA2A P29274 1/20 0.44
ADORA1 P30542 1/20 0.44
SRR Q9GZT4 2/20 0.44
PSAT1 Q9Y617 2/20 0.44
MME P08473 1/20 0.43
ACE P12821 1/20 0.43
CPA1 P15085 1/20 0.43
ACE2 Q9BYF1 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9468395 0.98 EPHX1 (0.50) EPHX1SIGMAR1ANPEPTAAR1CSNK1E
SCHEMBL172452 0.88 EPHX1 (0.67) EPHX1SIGMAR1ANPEPTAAR1CSNK1E
SCHEMBL3401432 0.88 EPHX1 (0.67) EPHX1SIGMAR1ANPEPTAAR1CSNK1E
SCHEMBL14471186 0.88 EPHX1 (0.67) EPHX1SIGMAR1ANPEPTAAR1CSNK1E
Bromide SCHEMBL6947335 0.86 EPHX1 (0.64) EPHX1SIGMAR1ANPEPTAAR1CSNK1E
Hydrochloric Acid SCHEMBL6659825 0.86 EPHX1 (0.64) EPHX1SIGMAR1ANPEPTAAR1CSNK1E
SCHEMBL2736211 0.85 EPHX1 (0.61) EPHX1SIGMAR1ANPEPTAAR1CSNK1E
SCHEMBL17906518 0.85 SLC6A4 (0.56) EPHX1SIGMAR1ANPEPTAAR1SLC6A2
SCHEMBL16945131 0.85 SLC6A4 (0.56) EPHX1SIGMAR1ANPEPTAAR1SLC6A2
SCHEMBL368694 0.81 EPHX1 (0.47) EPHX1SIGMAR1ANPEPTAAR1CSNK1E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3611160-A1 AMMONIUM CARBOXYLATE COMPOUND, CRYSTAL FORM AND AMORPHOUS SUBSTANCE THEREOF, AND PREPARATION METHOD THEREFOR Wuhan LL Science And Technology Development Co., Ltd. (CN) 2020-02-19 EP disclosed
US-5232946-A Promoting weight gain and reduction of blood sugar and fat deposits in animals, feed efficiency DR. KARL THOMAE GMBH (DE) 1993-08-03 US disclosed
EP-0400011-A1 NEW PHENYLETHANOLAMINES. BOEHRINGER INGELHEIM VETMED (DE) 1990-12-05 EP disclosed
EP-0375791-A1 Phenyl ethanol amines, their use as pharmaceutical compounds and as performance stimulants in animals, as well as processes for their preparation BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 1990-07-04 EP disclosed
WO-1990006299-A1 NEW PHENYLETHANOLAMINES BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 1990-06-14 WO disclosed