Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19084176 | 0.90 | GAA (0.39) | GAANAAACCR2BACE1F2 | |
| SCHEMBL17428278 | 0.90 | GAA (0.39) | CHRM2CHRM1GAANAAACCR2 | |
| SCHEMBL18583407 | 0.88 | GAA (0.38) | GAANAAACCR2BACE1F2 | |
| SCHEMBL16605375 | 0.84 | GAA (0.35) | GAANAAACCR2BACE1F2 | |
| SCHEMBL16604065 | 0.82 | GAA (0.34) | GAANAAACCR2F2F10 | |
| SCHEMBL16605376 | 0.82 | GAA (0.34) | GAANAAACCR2F2F10 | |
| SCHEMBL19084177 | 0.81 | GAA (0.41) | GAANAAABACE1F2F10 | |
| SCHEMBL17245220 | 0.81 | KMT2A (0.43) | NAAAF2RBACE1 | |
| SCHEMBL16605373 | 0.80 | KMT2A (0.37) | NAAABACE1 | |
| SCHEMBL17245218 | 0.80 | KMT2A (0.41) | NAAABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9700047-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-07-11 | — | — | US | disclosed |
| US-9700047-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-07-11 | — | — | US | disclosed |
| US-20170055528-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2017-03-02 | — | — | US | disclosed |
| US-20170055528-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2017-03-02 | — | — | US | disclosed |
| WO-2015171408-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2015-11-12 | — | — | WO | disclosed |
| US-20150322051-A1 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC | 2015-11-12 | — | — | US | disclosed |
| US-20150322051-A1 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC | 2015-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170055528-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | CYP4F12, CYP1A2, CYP4F2 | CHRM2 2949/4885CHRM1 3806/4885GAA 1084/4885 |
| US-20150322051-A1 | Macrocyclic picolinamides as fungicides | CYP4F12, CYP1A2, FKBP2 | CHRM2 2996/4885CHRM1 3603/4885GAA 1303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.