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FKBP2

Peptidyl-prolyl cis-trans isomerase FKBP2 · P26885 · FKBP2 on Sugi Atlas →

1,161 patent compounds predicted against FKBP2, 1,070 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL16937386 SCHEMBL16937386 1.00 1/20
SCHEMBL16949300 SCHEMBL16949300 1.00 1/20
SCHEMBL18122817 SCHEMBL18122817 1.00 1/20
SCHEMBL18354674 SCHEMBL18354674 1.00 1/20
SCHEMBL16594982 SCHEMBL16594982 0.98 1/20
SCHEMBL1107263 SCHEMBL1107263 0.86 1/20
SCHEMBL15791499 SCHEMBL15791499 0.86 1/20
SCHEMBL17231762 SCHEMBL17231762 0.86 1/20
SCHEMBL16937406 SCHEMBL16937406 0.85 1/20
SCHEMBL16948804 SCHEMBL16948804 0.85 1/20
SCHEMBL18354498 SCHEMBL18354498 0.85 1/20
SCHEMBL18120736 SCHEMBL18120736 0.85 1/20
SCHEMBL18122798 SCHEMBL18122798 0.83 1/20
SCHEMBL16937368 SCHEMBL16937368 0.83 1/20
SCHEMBL18122799 SCHEMBL18122799 0.83 1/20
SCHEMBL18354017 SCHEMBL18354017 0.83 1/20
SCHEMBL18359763 SCHEMBL18359763 0.83 1/20
SCHEMBL18120737 SCHEMBL18120737 0.83 1/20
SCHEMBL18122803 SCHEMBL18122803 0.81 1/20
SCHEMBL16586364 SCHEMBL16586364 0.81 1/20

Clinical trials — most relevant to FKBP2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Topical Metformin Emulgel VS Salicylic Acid Peeling in Treatment of Acne Vulgaris PHASE4UNKNOWN
Utilising Genotype Informed Bayesian Dosing of Tacrolimus in Children Post Solid Organ Transplantation. PHASE4RECRUITING
OPTImization of the Dose of tacroliMUS by Bayesian Prediction PHASE4COMPLETED
Canadian Cardiology de Novo Study: A Comparison Between Tacrolimus- and Cyclosporine- Based Immunoprophylactic Regimens PHASE3COMPLETED
Monoamine Transporters Genotypes: Risk of PTSD and Related Comorbidities PHASE3COMPLETED
Rapamycin for Immunosuppression and B Cell Modulation Post Stem Cell Transplant for Acute Lymphoblastic Leukemia (ALL) PHASE2COMPLETED
Cyclosporine For The Treatment Of COVID-19(+) PHASE2COMPLETED
FK506 (Tacrolimus) in Pulmonary Arterial Hypertension PHASE2COMPLETED
Temsirolimus With or Without Megestrol Acetate and Tamoxifen Citrate in Treating Patients With Advanced, Persistent, or Recurrent Endometrial Cancer PHASE2COMPLETED
Targeting Endoplasmic Reticulum Stress in Human Hypertension PHASE1/PHASE2RECRUITING
Neurosteroids for PTSD in Veterans PHASE2COMPLETED
A Phase I Study of IMC-A12 in Combination With Temsirolimus in Pediatric Patients With Recurrent or Refractory Solid Tumors PHASE1WITHDRAWN
Safety and Pharmacology of SNX-5422 Plus Carboplatin and Paclitaxel in Subjects With Solid Tumors PHASE1COMPLETED
Multimodal Neuroimaging of Alcohol Cues, Cortisol Response, and Compulsive Motivation EARLY_PHASE1COMPLETED
FKBP5 Methylation and Childhood Emotional Abuse in Complex Posttraumatic Stress Disorder: Investigating the Relationship and Its Predictive Role in Therapy Outcome nanCOMPLETED
Clinical Implications of FKBP5 in Stroke nanUNKNOWN
Torisel in Addition to Standard Chemotherapy With Radiation for Advanced Head and Neck Cancer nanWITHDRAWN
Quantification of GADD34 Expression in RA nanCOMPLETED
Cortisol, Hippocampus, and Insula in Anorexia Nervosa. nanRECRUITING
A Study on Psychopathological Progress of Early Schizophrenia-Like Disorder (SOPRES) nanUNKNOWN
Gene Polymorphisms in Tacrolimus Drug Interactions nanCOMPLETED
Genetic Predictors of Lithium Response in Bipolar Disorder nanCOMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq) nanRECRUITING
Evaluation of Interaction Between Immunosuppressive Drugs and Protein-bound Uremic Toxins in Renal Transplant Patients nanWITHDRAWN
The Partners Genetics Collaborative Study of Schizophrenia nanCOMPLETED
Identifying New Therapeutic Targets for Lupus Treatment nanCOMPLETED
Post-Deployment Afghanistan/Iraq Trauma Related Inventory of Traits (PATRIOT): Phase 1 (Feasibility Study) nanCOMPLETED
Expression of Fas Protein in Skin Biopsies of Participants With Scarring Alopecia nanCOMPLETED
Multi-level Molecular Profiling of High Acute Stress: a Clinical Study nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a FKBP2 binder may also engage these)

ProteinNameSimilarity
P45878 — 0.999 P45878 →
Q32PA9 — 0.996 Q32PA9 →
Q5ATN7 — 0.987 Q5ATN7 →
P0CP97 — 0.987 P0CP97 →
Q38935 — 0.986 Q38935 →
Q41649 — 0.984 Q41649 →
Q4WHX4 — 0.983 Q4WHX4 →
P20080 — 0.983 P20080 →
P32472 — 0.982 P32472 →
Q6BP84 — 0.982 Q6BP84 →
Q6CGG3 — 0.981 Q6CGG3 →
Q38936 — 0.980 Q38936 →
Q6CUZ8 — 0.980 Q6CUZ8 →
P0CP96 — 0.979 P0CP96 →
Q9Y680 — 0.978 Q9Y680 →
Q6FSC1 — 0.978 Q6FSC1 →
Q54SR7 — 0.976 Q54SR7 →
Q9FLB3 — 0.976 Q9FLB3 →
O54998 — 0.975 O54998 →
P26623 — 0.974 P26623 →
P0A9L4 — 0.974 P0A9L4 →
Q5RET2 — 0.974 Q5RET2 →
Q9D1M7 — 0.973 Q9D1M7 →
Q5U2T9 — 0.973 Q5U2T9 →
Q4IN00 — 0.972 Q4IN00 →
Q4W9R2 — 0.972 Q4W9R2 →
Q86ZF2 — 0.971 Q86ZF2 →
Q09734 — 0.971 Q09734 →
P0A0W2 — 0.970 P0A0W2 →
Q2UPT7 — 0.970 Q2UPT7 →