Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAMP1 | O60894 | 3/20 | 0.34 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17245237 | 0.89 | KMT2A (0.44) | KMT2AL3MBTL1KDM1AMAOB | |
| SCHEMBL17428279 | 0.88 | GAA (0.40) | KMT2AL3MBTL1KDM1AMAOBGAA | |
| SCHEMBL17245231 | 0.85 | KMT2A (0.43) | KMT2AL3MBTL1 | |
| SCHEMBL17898731 | 0.81 | GAA (0.39) | KMT2AGAA | |
| SCHEMBL17245225 | 0.80 | KMT2A (0.41) | KMT2AL3MBTL1 | |
| SCHEMBL19084164 | 0.80 | KMT2A (0.44) | KMT2AL3MBTL1 | |
| SCHEMBL16604078 | 0.79 | KMT2A (0.40) | KMT2AL3MBTL1KDM1AMAOBGAA | |
| SCHEMBL17428281 | 0.79 | KDM1A (0.41) | KMT2AL3MBTL1KDM1AMAOBGAA | |
| SCHEMBL17245217 | 0.79 | KMT2A (0.45) | KMT2AL3MBTL1 | |
| SCHEMBL17245235 | 0.78 | KMT2A (0.34) | KMT2AL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9700047-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-07-11 | — | — | US | disclosed |
| US-9700047-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-07-11 | — | — | US | disclosed |
| US-20170055528-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2017-03-02 | — | — | US | disclosed |
| US-20170055528-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2017-03-02 | — | — | US | disclosed |
| US-20150322051-A1 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC | 2015-11-12 | — | — | US | disclosed |
| US-20150322051-A1 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC | 2015-11-12 | — | — | US | disclosed |
| WO-2015171408-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2015-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170055528-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | CYP4F12, CYP1A2, CYP4F2 | KMT2A 2788/4885L3MBTL1 3646/4885KDM1A 1881/4885 |
| US-20150322051-A1 | Macrocyclic picolinamides as fungicides | CYP4F12, CYP1A2, FKBP2 | KMT2A 3234/4885L3MBTL1 3973/4885KDM1A 1840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.