SCHEMBL17245307

SCHEMBL17245307

c1ccc2cc(-n3c4ccccc4c4ccc5c6ccccc6n(-c6cccc7cnccc67)c5c43)ccc2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK10 P53779 9/20 0.38
▸ MAPK9 P45984 8/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ MAPK8 P45983 1/20 0.36
▸ CDK8 P49336 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ CYP3A4 P08684 1/20 0.35
▸ CYP2D6 P10635 1/20 0.35
▸ CYP2C9 P11712 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ MAPKAPK2 P49137 1/20 0.35
▸ CYP19A1 P11511 2/20 0.35
▸ CYP11B1 P15538 1/20 0.35
▸ CYP11B2 P19099 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17228169 0.88 MAPK10 (0.38) MAPK10MAPK9NPC1ALDH1A1POLB
SCHEMBL23233764 0.87 TDP1 (0.42) MAPK10MAPK9NPC1ALDH1A1POLB
SCHEMBL17245309 0.83 KDM4E (0.44) MAPK10MAPK9ALDH1A1KDM4ECYP19A1
SCHEMBL21671299 0.82 KDM4E (0.39) MAPK10MAPK9NPC1ALDH1A1POLB
SCHEMBL16484347 0.82 LMNA (0.47) NPC1ALDH1A1LMNACYP1A2CYP3A4
SCHEMBL10027551 0.82 KDM4E (0.44) MAPK10MAPK9NPC1ALDH1A1POLB
SCHEMBL27452201 0.81 TDP1 (0.38) MAPK10MAPK9NPC1ALDH1A1POLB
SCHEMBL18958072 0.81 KDM4E (0.40) MAPK10MAPK9MAPK8CYP1A2KDM4E
SCHEMBL26809883 0.80 KDM4E (0.44) MAPK10MAPK9NPC1ALDH1A1POLB
SCHEMBL17245501 0.80 CYP19A1 (0.36) MAPK10MAPK9MAPK8KDM4ECYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10573839-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-25 — — US disclosed
US-10020459-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-07-10 — — US disclosed
US-10020459-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-07-10 — — US disclosed
US-9818950-B2 Organic light-emitting devices SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-14 — — US disclosed
US-9818950-B2 Organic light-emitting devices SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-14 — — US disclosed
US-9748510-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-08-29 — — US disclosed
US-9748510-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-08-29 — — US disclosed
US-20160118590-A1 ORGANIC LIGHT-EMITTING DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-28 — — US disclosed
US-20160118590-A1 ORGANIC LIGHT-EMITTING DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-28 — — US disclosed
US-20150325801-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-12 — — US disclosed
US-20150325801-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-12 — — US disclosed
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