SCHEMBL17246592

SCHEMBL17246592

c1ccc2c(c1)sc1c2c2ccccc2c2c3ccccc3n(-c3ccc4cnccc4c3)c12

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CYP19A1 P11511 1/20 0.36
▸ TOP2A P11388 1/20 0.36
▸ MKNK2 Q9HBH9 1/20 0.33
▸ TDO2 P48775 1/20 0.33
▸ AKT1 P31749 2/20 0.32
▸ GRM4 Q14833 1/20 0.31
▸ MAPK10 P53779 3/20 0.31
▸ MAPK9 P45984 2/20 0.31
▸ CLK1 P49759 1/20 0.30
▸ PMM2 O15305 1/20 0.30
▸ MPI P34949 1/20 0.30
▸ PHOSPHO1 Q8TCT1 1/20 0.30
▸ TP53 P04637 1/20 0.30
▸ MAPT P10636 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17246594 0.93 CYP19A1 (0.36) CYP19A1TOP2AMKNK2TDO2AKT1
SCHEMBL18748634 0.90 PMM2 (0.36) PMM2MPIPHOSPHO1TP53MAPT
SCHEMBL17427577 0.87 PMM2 (0.40) MAPK10MAPK9PMM2MPIPHOSPHO1
SCHEMBL18748660 0.87 PMM2 (0.35) PMM2MPIPHOSPHO1TP53MAPT
SCHEMBL17705510 0.86 CYP19A1 (0.39) CYP19A1TOP2AMKNK2TDO2AKT1
SCHEMBL18748701 0.86 PMM2 (0.36) PMM2MPIPHOSPHO1TP53MAPT
SCHEMBL17705532 0.85 CYP19A1 (0.40) CYP19A1TOP2AMKNK2TDO2AKT1
SCHEMBL24767800 0.85 MAPK10 (0.34) CYP19A1TOP2AMAPK10MAPK9PMM2
SCHEMBL24767802 0.84 TOP2A (0.34) TOP2AMAPK10MAPK9PMM2MPI
SCHEMBL17246351 0.83 CYP19A1 (0.37) CYP19A1TOP2AMKNK2TDO2AKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10573839-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-25 — — US disclosed
US-10020459-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-07-10 — — US disclosed
US-9818950-B2 Organic light-emitting devices SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-14 — — US disclosed
US-9818950-B2 Organic light-emitting devices SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-14 — — US disclosed
US-9748510-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-08-29 — — US disclosed
US-9748510-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-08-29 — — US disclosed
US-20160118590-A1 ORGANIC LIGHT-EMITTING DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-28 — — US disclosed
US-20160118590-A1 ORGANIC LIGHT-EMITTING DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-28 — — US disclosed
US-20150325801-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-12 — — US disclosed
US-20150325801-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-12 — — US disclosed
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