SCHEMBL24767802

SCHEMBL24767802

c1ccc2cc3cc(-n4c5ccccc5c5c6ccncc6c6sc7ccccc7c6c54)ccc3cc2c1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ TOP2A P11388 1/20 0.34
▸ MAPK10 P53779 7/20 0.32
▸ MAPK9 P45984 6/20 0.32
▸ PMM2 O15305 1/20 0.31
▸ MPI P34949 1/20 0.31
▸ PHOSPHO1 Q8TCT1 1/20 0.31
▸ MAPK8 P45983 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24767800 0.97 MAPK10 (0.34) TOP2AMAPK10MAPK9PMM2MPI
SCHEMBL24767801 0.92 TOP2A (0.34) TOP2A
SCHEMBL24767783 0.86 TOP2A (0.33) TOP2A
SCHEMBL24768833 0.86 ATM (0.36) TOP2A
SCHEMBL18960866 0.86 PMM2 (0.39) MAPK10MAPK9PMM2MPIPHOSPHO1
SCHEMBL24768814 0.85 TOP2A (0.31) TOP2A
SCHEMBL24768917 0.85 CYP17A1 (0.36) TOP2AMAPK10MAPK9MAPK8
SCHEMBL17246592 0.84 CYP19A1 (0.36) TOP2AMAPK10MAPK9PMM2MPI
SCHEMBL24767791 0.84 ALOX12 (0.34) TOP2A
SCHEMBL18748701 0.84 PMM2 (0.36) PMM2MPIPHOSPHO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220251077-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. (TW) 2022-08-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220251077-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME SLCO4C1, SLCO2A1, SLCO2B1 TOP2A 4331/4885MAPK10 2408/4885MAPK9 2000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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