SCHEMBL17246702

SCHEMBL17246702

c1ccc(-c2nc(-c3ccccc3)nc(-n3c4ccc(-c5ccc6c(c5)c5cc(-c7ccc8c(c7)c7cc9oc%10ccccc%10c9cc7n8-c7ccccc7)ccc5n6-c5ccccc5)cc4c4cc5c(cc43)c3ccccc3n5-c3ccccc3)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PTGER4 P35408 1/20 0.35
CHEK2 O96017 1/20 0.33
AHR P35869 1/20 0.32
SIRT2 Q8IXJ6 1/20 0.32
SIRT1 Q96EB6 1/20 0.32
PLA2G2A P14555 2/20 0.32
PLA2G4A P47712 2/20 0.32
TSHR P16473 1/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPY5R Q15761 1/20 0.31
PTPN1 P18031 1/20 0.31
PLA2G10 O15496 1/20 0.31
TSPO P30536 1/20 0.30
KMT2A Q03164 1/20 0.30
IL1R1 P14778 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17246705 0.99 KDM4E (0.38) KDM4EATML3MBTL1PTGER4CHEK2
SCHEMBL22192559 0.96 KDM4E (0.42) KDM4EATML3MBTL1PTGER4CHEK2
SCHEMBL22192391 0.96 KDM4E (0.42) KDM4EATML3MBTL1PTGER4CHEK2
SCHEMBL19830409 0.95 KDM4E (0.38) KDM4EATML3MBTL1PTGER4CHEK2
SCHEMBL19830659 0.95 KDM4E (0.38) KDM4EATML3MBTL1PTGER4CHEK2
SCHEMBL16406775 0.95 KDM4E (0.38) KDM4EATML3MBTL1PTGER4CHEK2
SCHEMBL27324668 0.95 KDM4E (0.39) KDM4EATML3MBTL1PTGER4CHEK2
SCHEMBL16406764 0.95 KDM4E (0.39) KDM4EATML3MBTL1PTGER4CHEK2
SCHEMBL27443753 0.95 L3MBTL1 (0.41) KDM4EATML3MBTL1PTGER4CHEK2
SCHEMBL16811466 0.95 KDM4E (0.41) KDM4EATML3MBTL1PTGER4CHEK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10573839-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-25 US disclosed
US-10020459-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-07-10 US disclosed
US-10020459-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-07-10 US disclosed
US-9818950-B2 Organic light-emitting devices SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-14 US disclosed
US-9818950-B2 Organic light-emitting devices SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-14 US disclosed
US-9748510-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-08-29 US disclosed
US-9748510-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-08-29 US disclosed
US-20160118590-A1 ORGANIC LIGHT-EMITTING DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-28 US disclosed
US-20160118590-A1 ORGANIC LIGHT-EMITTING DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-28 US disclosed
US-20150325801-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-12 US disclosed
US-20150325801-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-12 US disclosed