Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17080933 | 0.93 | MEN1 (0.59) | LTA4HAHRMEN1KMT2AABCG2 | |
| SCHEMBL16288430 | 0.85 | NQO1 (0.56) | LTA4HAHRKMT2ARAB9ATP53 | |
| SCHEMBL11854557 | 0.79 | ESR1 (0.52) | LTA4HAHRMEN1KMT2ANR5A1 | |
| SCHEMBL14198010 | 0.79 | NR5A1 (0.61) | LTA4HNR5A1PLA2G4AGAARAB9A | |
| SCHEMBL9915594 | 0.78 | AHR (0.73) | LTA4HAHRMEN1KMT2AABCG2 | |
| SCHEMBL8713169 | 0.78 | MAPT (0.39) | AHRMEN1KMT2ACYP1A2TSHR | |
| SCHEMBL19994224 | 0.77 | TP53 (0.53) | ABCG2PLA2G4ATP53TSHR | |
| SCHEMBL14964565 | 0.77 | MAPT (0.62) | LTA4HAHRMEN1KMT2ANR5A1 | |
| SCHEMBL9625283 | 0.77 | CYP2D6 (0.53) | LTA4HAHRMEN1KMT2ANR5A1 | |
| SCHEMBL141697 | 0.77 | KDM4E (0.53) | ABCG2PLA2G4ATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160143878-A1 | ANTIBACTERIAL AGENT | JUNTENDO EDUCATIONAL FOUNDATION (JP) | 2016-05-26 | — | — | US | disclosed |
| US-20150322033-A1 | ANTIBACTERIAL AGENT | JUNTENDO EDUCATIONAL FOUNDATION (JP) | 2015-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160143878-A1 | ANTIBACTERIAL AGENT | MRPL21, Q6ZSR9, NQO2 | LTA4H 2135/4885AHR 446/4885MEN1 4060/4885 |
| US-20150322033-A1 | ANTIBACTERIAL AGENT | Q6ZSR9, MRPL21, NQO2 | LTA4H 2129/4885AHR 377/4885MEN1 4104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.